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Zaragoza F. One-Step Conversion of Methyl Ketones to Acyl Chlorides. J Org Chem. 2015;80(20):10370-4doi: 10.1021/acs.joc.5b01707.
Zaragoza, F. (2015). One-Step Conversion of Methyl Ketones to Acyl Chlorides. The Journal of organic chemistry, 80(20), 10370-4. https://doi.org/10.1021/acs.joc.5b01707
Zaragoza, Florencio. "One-Step Conversion of Methyl Ketones to Acyl Chlorides." The Journal of organic chemistry vol. 80,20 (2015): 10370-4. doi: https://doi.org/10.1021/acs.joc.5b01707
Zaragoza F. One-Step Conversion of Methyl Ketones to Acyl Chlorides. J Org Chem. 2015 Oct 16;80(20):10370-4. doi: 10.1021/acs.joc.5b01707. Epub 2015 Oct 02. PMID: 26427718.
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J Org Chem. 2015 Oct 16;80(20):10370-4. doi: 10.1021/acs.joc.5b01707. Epub 2015 Oct 02.

One-Step Conversion of Methyl Ketones to Acyl Chlorides.

The Journal of organic chemistry

Florencio Zaragoza

Affiliations

  1. Lonza AG , Rottenstrasse 6, CH-3930 Visp, Switzerland.

PMID: 26427718 DOI: 10.1021/acs.joc.5b01707

Abstract

Treatment of aromatic and heteroaromatic methyl ketones with sulfur monochloride and catalytic amounts of pyridine in refluxing chlorobenzene leads to the formation of acyl chlorides. Both electron-rich and electron-poor aryl methyl ketones can be used as starting materials. The resulting C1-byproduct depends on the precise reaction conditions chosen.

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