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Fogelman JP, Stevenson ML, Ashinoff R, et al. Idiopathic Flushing with Dysesthesia: Treatment with the 585nm Pulsed Dye Laser. J Clin Aesthet Dermatol. 2015;8(8):36-41
Fogelman, J. P., Stevenson, M. L., Ashinoff, R., & Soter, N. A. (2015). Idiopathic Flushing with Dysesthesia: Treatment with the 585nm Pulsed Dye Laser. The Journal of clinical and aesthetic dermatology, 8(8), 36-41.
Fogelman, Joshua P, et al. "Idiopathic Flushing with Dysesthesia: Treatment with the 585nm Pulsed Dye Laser." The Journal of clinical and aesthetic dermatology vol. 8,8 (2015): 36-41.
Fogelman JP, Stevenson ML, Ashinoff R, Soter NA. Idiopathic Flushing with Dysesthesia: Treatment with the 585nm Pulsed Dye Laser. J Clin Aesthet Dermatol. 2015 Aug;8(8):36-41. PMID: 26345489; PMCID: PMC4557849.
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J Clin Aesthet Dermatol. 2015 Aug;8(8):36-41.

Idiopathic Flushing with Dysesthesia: Treatment with the 585nm Pulsed Dye Laser.

The Journal of clinical and aesthetic dermatology

Joshua P Fogelman, Mary L Stevenson, Robin Ashinoff, Nicholas A Soter

Affiliations

  1. Department of Dermatology, Columbia University, and Dermatology Center of Rockland, P.C., New York, New York, and Orangeburg, New York;
  2. Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York;
  3. Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York; ; Hackensack University Medical Center, Hackensack, New Jersey.

PMID: 26345489 PMCID: PMC4557849

Abstract

OBJECTIVE: The purpose of this study was to analyze the efficacy and safety of the 585nm pulsed dye laser for the treatment of idiopathic flushing with dysesthesia.

DESIGN: This was a retrospective study of patients treated with a 585nm pulsed dye laser with fluences ranging from 3.5 to 7.5J/cm(2) (purpura threshold fluences), a pulse duration of 450μsec, and a spot size of 5 or 10mm.

SETTING: The Ronald 0. Perelman Department of Dermatology at New York University Medical Center.

PARTICIPANTS: Ten adult subjects who presented with flushing with dysesthesia.

MEASUREMENTS: PARTICIPANTS subjectively evaluated the decrease in dysesthesia and the number of flushing episodes. The objective response to treatment was evaluated by a single physician using pre- and postoperative photographs. The severity of postoperative erythema was compared with baseline using an ordinal scale ranging from zero (resolution of erythema) to four (76-100% of baseline erythema).

RESULTS: The mean number of treatments received by the subjects was seven. The mean fluence was 6.66J/cm(2). Subjectively, 100 percent of subjects reported a decrease in dysethesia and the number of flushing episodes. OBJECTIVEly, subjects demonstrated at least a 62.5-percent reduction in erythema.

CONCLUSION: Laser surgery provided subjective relief of dysesthesia and decreased the number of flushing episodes with a greater than 62-percent objective reduction in the severity of erythema. The 585nm pulsed dye laser is a safe, efficacious treatment for the signs and symptoms of idiopathic flushing with dysesthesia.

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