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Coelho Júnior HJ, Aguiar Sda S, Gonçalves Ide O, et al. Sarcopenia Is Associated with High Pulse Pressure in Older Women. J Aging Res. 2015;2015:109824doi: 10.1155/2015/109824.
Coelho Júnior, H. J., Aguiar, S. d. a. . S., Gonçalves, I. d. e. . O., Sampaio, R. A., Uchida, M. C., Moraes, M. R., & Asano, R. Y. (2015). Sarcopenia Is Associated with High Pulse Pressure in Older Women. Journal of aging research, 2015109824. https://doi.org/10.1155/2015/109824
Coelho Júnior, Hélio José, et al. "Sarcopenia Is Associated with High Pulse Pressure in Older Women." Journal of aging research vol. 2015 (2015): 109824. doi: https://doi.org/10.1155/2015/109824
Coelho Júnior HJ, Aguiar Sda S, Gonçalves Ide O, Sampaio RA, Uchida MC, Moraes MR, Asano RY. Sarcopenia Is Associated with High Pulse Pressure in Older Women. J Aging Res. 2015;2015:109824. doi: 10.1155/2015/109824. Epub 2015 Aug 05. PMID: 26346157; PMCID: PMC4541009.
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J Aging Res. 2015;2015:109824. doi: 10.1155/2015/109824. Epub 2015 Aug 05.

Sarcopenia Is Associated with High Pulse Pressure in Older Women.

Journal of aging research

Hélio José Coelho Júnior, Samuel da Silva Aguiar, Ivan de Oliveira Gonçalves, Ricardo Aurélio Carvalho Sampaio, Marco Carlos Uchida, Milton Rocha Moraes, Ricardo Yukio Asano

Affiliations

  1. School of Physical Education, State University of Campinas, 130883851 Campinas, Brazil ; Center of Health Sciences, University of Mogi das Cruzes, 08770-490 Mogi das Cruzes, Brazil.
  2. Center of Health Sciences, University of Mogi das Cruzes, 08770-490 Mogi das Cruzes, Brazil ; Graduate Program on Physical Education, Catholic University of Brasilia, 71966-700 Brasilia, Brazil.
  3. Community Center for Older People of Poá, Poá, Brazil.
  4. School of Physical Education, State University of Campinas, 130883851 Campinas, Brazil.
  5. Graduate Program on Physical Education, Catholic University of Brasilia, 71966-700 Brasilia, Brazil.
  6. Center of Health Sciences, University of Mogi das Cruzes, 08770-490 Mogi das Cruzes, Brazil ; School of Sciences and Letters of Bragança Paulista, SP, Brazil.

PMID: 26346157 PMCID: PMC4541009 DOI: 10.1155/2015/109824

Abstract

Introduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown a relationship between changes in muscle mass and the cardiovascular system. However, this relationship has not been fully elucidated. Methods. One hundred and thirty community-dwelling Brazilian older women (65.4 ± 6.3 years) were recruited to participate in this study. Data on body composition (via bioelectrical impedance measurements), cardiovascular parameters (using an automatic and noninvasive monitor), and muscle function (using a 3-meter gait speed test) were measured. Results. Sarcopenic older women (n = 43) presented higher levels of pulse pressure (PP) (60.3 ± 2.6 mmHg) and lower muscle function (0.5 ± 0.0 m/s) compared with nonsarcopenic subjects (n = 87) (53.7 ± 1.5 mmHg; 0.9 ± 0.0 m/s) (P < 0.05). Linear regression analysis demonstrated a significantly negative association between skeletal muscle index (SMI) and PP levels (β = -226, P < 0.05). Furthermore, sarcopenic older women showed a 3.1-fold increased risk of having higher PP levels compared with nonsarcopenic women (IC = 1.323-7.506) (P < 0.05). Conclusion. Sarcopenic older women showed lower muscle function and higher cardiovascular risk due to increased PP levels compared with nonsarcopenic subjects.

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