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Sriprasert I, Suerungruang S, Athilarp P, et al. Efficacy of Acupuncture versus Combined Oral Contraceptive Pill in Treatment of Moderate-to-Severe Dysmenorrhea: A Randomized Controlled Trial. Evid Based Complement Alternat Med. 2015;2015:735690doi: 10.1155/2015/735690.
Sriprasert, I., Suerungruang, S., Athilarp, P., Matanasarawoot, A., & Teekachunhatean, S. (2015). Efficacy of Acupuncture versus Combined Oral Contraceptive Pill in Treatment of Moderate-to-Severe Dysmenorrhea: A Randomized Controlled Trial. Evidence-based complementary and alternative medicine : eCAM, 2015735690. https://doi.org/10.1155/2015/735690
Sriprasert, Intira, et al. "Efficacy of Acupuncture versus Combined Oral Contraceptive Pill in Treatment of Moderate-to-Severe Dysmenorrhea: A Randomized Controlled Trial." Evidence-based complementary and alternative medicine : eCAM vol. 2015 (2015): 735690. doi: https://doi.org/10.1155/2015/735690
Sriprasert I, Suerungruang S, Athilarp P, Matanasarawoot A, Teekachunhatean S. Efficacy of Acupuncture versus Combined Oral Contraceptive Pill in Treatment of Moderate-to-Severe Dysmenorrhea: A Randomized Controlled Trial. Evid Based Complement Alternat Med. 2015;2015:735690. doi: 10.1155/2015/735690. Epub 2015 Aug 04. PMID: 26346199; PMCID: PMC4539461.
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Evid Based Complement Alternat Med. 2015;2015:735690. doi: 10.1155/2015/735690. Epub 2015 Aug 04.

Efficacy of Acupuncture versus Combined Oral Contraceptive Pill in Treatment of Moderate-to-Severe Dysmenorrhea: A Randomized Controlled Trial.

Evidence-based complementary and alternative medicine : eCAM

Intira Sriprasert, Suparerk Suerungruang, Porntip Athilarp, Anuchart Matanasarawoot, Supanimit Teekachunhatean

Affiliations

  1. Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
  2. Health Promotion Center Region 10, Department of Health, Ministry of Public Health, Chiang Mai 50100, Thailand.
  3. Center of Thai Traditional and Complementary Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
  4. Department of Family Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
  5. Center of Thai Traditional and Complementary Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand ; Department of Pharmacology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

PMID: 26346199 PMCID: PMC4539461 DOI: 10.1155/2015/735690

Abstract

This open-label randomized controlled trial was designed to compare the efficacy of acupuncture and combined oral contraceptive (COC) pill in treating moderate-to-severe primary dysmenorrhea. Fifty-two participants were randomly assigned to receive either acupuncture (n = 27) or COC (n = 25) for three menstrual cycles. Mefenamic acid was prescribed as a recue analgesic drug with both groups. The statistical approach used for efficacy and safety assessments was intention-to-treat analysis. By the end of the study, both treatments had resulted in significant improvement over baselines in all outcomes, that is, maximal dysmenorrhea pain scores, days suffering from dysmenorrhea, amount of rescue analgesic used, and quality of life assessed by SF-36 questionnaire. Over the three treatment cycles, COC caused greater reduction in maximal pain scores than acupuncture, while improvements in the remaining outcomes were comparable. Responders were defined as participants whose maximal dysmenorrhea pain scores decreased at least 33% below their baseline. Response rates following both interventions at the end of the study were not statistically different. Acupuncture commonly caused minimal local side effects but did not cause any hormone-related side effects as did COC. In conclusion, acupuncture is an alternative option for relieving dysmenorrhea, especially when COC is not a favorable choice.

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