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MacNeil LT, Pons C, Arda HE, et al. Transcription Factor Activity Mapping of a Tissue-Specific . Cell Syst. 2015;1(2):152-162doi: 10.1016/j.cels.2015.08.003.
MacNeil, L. T., Pons, C., Arda, H. E., Giese, G. E., Myers, C. L., & Walhout, A. J. (2015). Transcription Factor Activity Mapping of a Tissue-Specific . Cell systems, 1(2), 152-162. https://doi.org/10.1016/j.cels.2015.08.003
MacNeil, Lesley T, et al. "Transcription Factor Activity Mapping of a Tissue-Specific ." Cell systems vol. 1,2 (2015): 152-162. doi: https://doi.org/10.1016/j.cels.2015.08.003
MacNeil LT, Pons C, Arda HE, Giese GE, Myers CL, Walhout AJ. Transcription Factor Activity Mapping of a Tissue-Specific . Cell Syst. 2015 Aug 26;1(2):152-162. doi: 10.1016/j.cels.2015.08.003. PMID: 26430702; PMCID: PMC4584425.
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Cell Syst. 2015 Aug 26;1(2):152-162. doi: 10.1016/j.cels.2015.08.003.

Transcription Factor Activity Mapping of a Tissue-Specific .

Cell systems

Lesley T MacNeil, Carles Pons, H Efsun Arda, Gabrielle E Giese, Chad L Myers, Albertha J M Walhout

Affiliations

  1. Program in Systems Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA ; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
  2. Department of Computer Science and Engineering, University of Minnesota-Twin Cities, Minneapolis, MN 55455, USA.
  3. Program in Systems Biology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

PMID: 26430702 PMCID: PMC4584425 DOI: 10.1016/j.cels.2015.08.003

Abstract

A wealth of physical interaction data between transcription factors (TFs) and DNA has been generated, but these interactions often do not have apparent regulatory consequences. Thus, equating physical interaction data with gene regulatory networks (GRNs) is problematic. Here, we comprehensively assay TF activity, rather than binding, to construct a network of gene regulatory interactions in the

References

  1. Mol Biosyst. 2012 Nov;8(11):2932-6 - PubMed
  2. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12049-54 - PubMed
  3. BMC Biol. 2015 Jan 20;13:4 - PubMed
  4. PLoS One. 2013;8(3):e59719 - PubMed
  5. PLoS Genet. 2011 May;7(5):e1002074 - PubMed
  6. Genome Biol. 2005;6(13):R110 - PubMed
  7. Mol Cell. 2013 Jul 11;51(1):116-27 - PubMed
  8. Cell. 2006 Jun 16;125(6):1193-205 - PubMed
  9. Nature. 2014 Aug 28;512(7515):400-5 - PubMed
  10. Bioinformatics. 2007 Jul 1;23(13):i305-12 - PubMed
  11. Methods Enzymol. 2000;328:575-92 - PubMed
  12. RNA. 2003 Jul;9(7):847-57 - PubMed
  13. Mol Cell. 2006 Nov 17;24(4):593-602 - PubMed
  14. Mol Syst Biol. 2010 May 11;6:367 - PubMed
  15. Nat Genet. 2003 May;34(1):35-41 - PubMed
  16. Dev Biol. 2007 Feb 15;302(2):627-45 - PubMed
  17. Genome Biol. 2011;12(4):109 - PubMed
  18. J Gen Physiol. 2005 Oct;126(4):379-92 - PubMed
  19. Genome Res. 2004 Oct;14(10B):2169-75 - PubMed
  20. Nat Methods. 2011 Oct 30;8(12):1065-70 - PubMed
  21. Genome Res. 2004 Oct;14(10B):2162-8 - PubMed
  22. Nat Genet. 2007 May;39(5):683-7 - PubMed
  23. Nature. 2012 Sep 6;489(7414):57-74 - PubMed
  24. Nat Methods. 2011 Oct 30;8(12):1059-64 - PubMed
  25. Nature. 2004 Sep 2;431(7004):99-104 - PubMed
  26. Mol Syst Biol. 2009;5:294 - PubMed
  27. Genes Dev. 2007 Oct 1;21(19):2448-60 - PubMed
  28. Dev Biol. 2009 Mar 15;327(2):551-65 - PubMed
  29. Cell. 2013 Mar 28;153(1):240-52 - PubMed
  30. Biochem Biophys Res Commun. 2011 Oct 7;413(4):515-20 - PubMed
  31. Genome Res. 2012 Jul;22(7):1282-94 - PubMed
  32. Cell. 2013 Mar 28;153(1):253-66 - PubMed
  33. Genetics. 2001 Mar;157(3):1217-26 - PubMed
  34. Nature. 2003 Jul 17;424(6946):277-83 - PubMed
  35. Development. 2006 Jan;133(2):287-95 - PubMed
  36. Cell. 2015 Apr 23;161(3):661-73 - PubMed
  37. Nature. 2014 Aug 28;512(7515):445-8 - PubMed
  38. Dev Cell. 2006 Jun;10 (6):797-807 - PubMed
  39. Curr Biol. 2013 Apr 8;23(7):607-13 - PubMed
  40. Nat Methods. 2011 Oct 30;8(12):1053-5 - PubMed
  41. Development. 1994 Sep;120(9):2359-68 - PubMed
  42. Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14724-31 - PubMed
  43. Cell. 2014 Apr 24;157(3):740-52 - PubMed
  44. Genes Dev. 2008 Oct 1;22(19):2651-63 - PubMed
  45. Nature. 2003 Jan 16;421(6920):231-7 - PubMed

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