Display options
Cite
Lee DJ, Ko D, Yoo EJ. Rhodium(II)-Catalyzed Cycloaddition Reactions of Non-classical 1,5-Dipoles for the Formation of Eight-Membered Heterocycles. Angew Chem Int Ed Engl. 2015;54(46):13715-8doi: 10.1002/anie.201506764.
Lee, D. J., Ko, D., & Yoo, E. J. (2015). Rhodium(II)-Catalyzed Cycloaddition Reactions of Non-classical 1,5-Dipoles for the Formation of Eight-Membered Heterocycles. Angewandte Chemie (International ed. in English), 54(46), 13715-8. https://doi.org/10.1002/anie.201506764
Lee, Dong Jin, et al. "Rhodium(II)-Catalyzed Cycloaddition Reactions of Non-classical 1,5-Dipoles for the Formation of Eight-Membered Heterocycles." Angewandte Chemie (International ed. in English) vol. 54,46 (2015): 13715-8. doi: https://doi.org/10.1002/anie.201506764
Lee DJ, Ko D, Yoo EJ. Rhodium(II)-Catalyzed Cycloaddition Reactions of Non-classical 1,5-Dipoles for the Formation of Eight-Membered Heterocycles. Angew Chem Int Ed Engl. 2015 Nov 09;54(46):13715-8. doi: 10.1002/anie.201506764. Epub 2015 Sep 17. PMID: 26376924.
Copy Download .nbib Format: NLM
Share it on

Angew Chem Int Ed Engl. 2015 Nov 09;54(46):13715-8. doi: 10.1002/anie.201506764. Epub 2015 Sep 17.

Rhodium(II)-Catalyzed Cycloaddition Reactions of Non-classical 1,5-Dipoles for the Formation of Eight-Membered Heterocycles.

Angewandte Chemie (International ed. in English)

Dong Jin Lee, Donguk Ko, Eun Jeong Yoo

Affiliations

  1. Department of Chemistry, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, 200-701 (Republic of Korea).
  2. Department of Chemistry, Kangwon National University, 1 Kangwondaehak-gil, Chuncheon, 200-701 (Republic of Korea). [email protected].

PMID: 26376924 DOI: 10.1002/anie.201506764

Abstract

A new type of intermolecular rhodium(II)-catalyzed [5+3] cycloaddition has been developed. This higher-order cycloaddition between pyridinium zwitterion 1,5-dipole equivalents and enol diazoacetates enables the formation of eight-membered heterocyclic skeletons, which are otherwise difficult to construct. The optimized cycloaddition occurs efficiently under mild conditions with a wide range of pyridinium zwitterions and with high functional-group tolerance.

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords: cycloaddition; eight-membered heterocycles; homogeneous catalysis; rhodium; zwitterions

Publication Types