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Asian Spine J. 2015 Oct;9(5):798-802. doi: 10.4184/asj.2015.9.5.798. Epub 2015 Sep 22.

Lumbar Cryptococcal Osteomyelitis Mimicking Metastatic Tumor.

Asian spine journal

Hyun Seok Joo, Jung-Ki Ha, Chang Ju Hwang, Dong-Ho Lee, Choon Sung Lee, Jae Hwan Cho

Affiliations

  1. Department of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

PMID: 26435802 PMCID: PMC4591455 DOI: 10.4184/asj.2015.9.5.798

Abstract

Cryptococcus is an encapsulated, yeast-like fungus that rarely causes infection in immunocompetent patients. We present the case report of a 66-year-old female patient with a history of rectal cancer with an isolated lumbar vertebral cryptococcosis proven by biopsy performed during operation. The patient was not an immunocompromised host and did not have any other risk factors except the history of cured rectal cancer. The presumptive diagnosis based on imaging studies was metastatic spine cancer, so operation was performed. However, cryptococcal osteomyelitis was diagnosed in the pathologic examination. This case report emphasizes that we should be aware that lumbar cryptococcosis can be a rare cause of mimicking lesions with metastatic cancer.

Keywords: Cryptococcus; Lumbar vertebrae; Neoplasm metastasis; Osteomyelitis

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