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Yang M, Fujino T. Ammonium Ion Exchanged Zeolite for Laser Desorption/Ionization Mass Spectrometry of Phosphorylated Peptides. Int J Anal Chem. 2015;2015:513761doi: 10.1155/2015/513761.
Yang, M., & Fujino, T. (2015). Ammonium Ion Exchanged Zeolite for Laser Desorption/Ionization Mass Spectrometry of Phosphorylated Peptides. International journal of analytical chemistry, 2015513761. https://doi.org/10.1155/2015/513761
Yang, Mengrui, and Fujino, Tatsuya. "Ammonium Ion Exchanged Zeolite for Laser Desorption/Ionization Mass Spectrometry of Phosphorylated Peptides." International journal of analytical chemistry vol. 2015 (2015): 513761. doi: https://doi.org/10.1155/2015/513761
Yang M, Fujino T. Ammonium Ion Exchanged Zeolite for Laser Desorption/Ionization Mass Spectrometry of Phosphorylated Peptides. Int J Anal Chem. 2015;2015:513761. doi: 10.1155/2015/513761. Epub 2015 Sep 13. PMID: 26448749; PMCID: PMC4584054.
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Int J Anal Chem. 2015;2015:513761. doi: 10.1155/2015/513761. Epub 2015 Sep 13.

Ammonium Ion Exchanged Zeolite for Laser Desorption/Ionization Mass Spectrometry of Phosphorylated Peptides.

International journal of analytical chemistry

Mengrui Yang, Tatsuya Fujino

Affiliations

  1. Institute of Quality Standard and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China ; Department of Chemistry, Graduate School of Science and Engineering, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0379, Japan.
  2. Department of Chemistry, Graduate School of Science and Engineering, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0379, Japan.

PMID: 26448749 PMCID: PMC4584054 DOI: 10.1155/2015/513761

Abstract

α-Cyano-4-hydroxycinnamic acid (CHCA), an organic matrix molecule for matrix-assisted laser desorption/ionization mass spectrometry, was adsorbed to NH4 (+)-type zeolite surface, and this new matrix was used for the detection of low-molecular-weight compounds. It was found that this matrix could simplify the mass spectrum in the low-molecular-weight region and prevent interference from fragments and alkali metal ion adducted species. CHCA adsorbed to NH4 (+)-type ZSM5 zeolite (CHCA/NH4ZSM5) was used to measure atropine and aconitine, two toxic alkaloids in plants. In addition, CHCA/NH4ZSM5 enabled us to detect phosphorylated peptides; peaks of the protonated peptides had higher intensities than the peaks observed using CHCA only.

References

  1. Anal Sci. 2012;28(9):901-4 - PubMed
  2. J Am Soc Mass Spectrom. 2009 Nov;20(11):2167-73 - PubMed
  3. Anal Sci. 2008;24(11):1497-500 - PubMed
  4. Anal Sci. 2010;26(7):743-8 - PubMed
  5. Anal Sci. 2013;29(11):1035-9 - PubMed
  6. Forensic Sci Int. 2009 Mar 10;185(1-3):1-9 - PubMed
  7. J Am Soc Mass Spectrom. 2010 Nov;21(11):1930-9 - PubMed
  8. J Am Soc Mass Spectrom. 1999 Jan;10(1):35-44 - PubMed
  9. J Hazard Mater. 2008 Dec 30;160(2-3):371-5 - PubMed

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