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Pasquali PJ, Teixeira ML, de Oliveira TA, et al. Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans. Int J Biomater. 2015;2015:121286doi: 10.1155/2015/121286.
Pasquali, P. J., Teixeira, M. L., de Oliveira, T. A., de Macedo, L. G., Aloise, A. C., & Pelegrine, A. A. (2015). Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans. International journal of biomaterials, 2015121286. https://doi.org/10.1155/2015/121286
Pasquali, Paulo José, et al. "Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans." International journal of biomaterials vol. 2015 (2015): 121286. doi: https://doi.org/10.1155/2015/121286
Pasquali PJ, Teixeira ML, de Oliveira TA, de Macedo LG, Aloise AC, Pelegrine AA. Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans. Int J Biomater. 2015;2015:121286. doi: 10.1155/2015/121286. Epub 2015 Oct 12. PMID: 26543482; PMCID: PMC4620258.
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Int J Biomater. 2015;2015:121286. doi: 10.1155/2015/121286. Epub 2015 Oct 12.

Maxillary Sinus Augmentation Combining Bio-Oss with the Bone Marrow Aspirate Concentrate: A Histomorphometric Study in Humans.

International journal of biomaterials

Paulo José Pasquali, Marcelo Lucchesi Teixeira, Thiago Altro de Oliveira, Luis Guilherme Scavone de Macedo, Antonio Carlos Aloise, André Antonio Pelegrine

Affiliations

  1. Department of Implant Dentistry, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil.
  2. Department of Prosthodontics, São Leopoldo Mandic Dental School, 13 José Rocha Junqueira Street, 13045-755 Campinas, Brazil.

PMID: 26543482 PMCID: PMC4620258 DOI: 10.1155/2015/121286

Abstract

Purpose. To investigate the regenerative results obtained with the association of bone marrow aspirate concentrate using the Bone Marrow Aspirate Concentrate (BMAC) method to a xenogeneic bone graft (Bio-Oss) in sinus floor elevation. Materials and Methods. Using a randomized controlled study design in eight consecutive patients (age of 55.4 ± 9.2 years), 16 sinus floor lift procedures were performed with Bio-Oss alone (control group, CG, n = 8) or combined with bone marrow aspirate concentrate obtained via the BMAC method (test group, TG, n = 8). Six months after the grafting procedures, bone biopsies were harvested during implant placement and were analyzed by histomorphometry. Results. Histomorphometric analysis revealed a significantly higher amount (p < 0.05) of vital mineralized tissue in TG when compared to the CG (55.15 ± 20.91% and 27.30 ± 5.55%, resp.). For nonvital mineralized tissue, TG presented a statistically higher level of Bio-Oss resorption (p < 0.05) when compared with the CG (6.32 ± 12.03% and 22.79 ± 9.60%, resp.). Both groups (TG and CG) showed no significantly different levels (p > 0.05) of nonmineralized tissue (38.53 ± 13.08% and 49.90 ± 7.64%, resp.). Conclusion. The use of bone marrow concentrate obtained by BMAC method increased bone formation in sinus lift procedures.

References

  1. Clin Oral Implants Res. 1997 Apr;8(2):117-24 - PubMed
  2. Int J Oral Maxillofac Surg. 2007 Sep;36(9):822-7 - PubMed
  3. J Periodontol. 2009 Dec;80(12):1920-7 - PubMed
  4. Clin Implant Dent Relat Res. 2001;3(2):87-96 - PubMed
  5. Clin Orthop Relat Res. 1985 Nov;(200):322-42 - PubMed
  6. Gen Dent. 2011 Sep-Oct;59(5):e200-5 - PubMed
  7. Acta Orthop. 2008 Jun;79(3):445-8 - PubMed
  8. Ann Periodontol. 2003 Dec;8(1):328-43 - PubMed
  9. Tissue Eng. 2003 Feb;9(1):95-103 - PubMed
  10. Clin Oral Implants Res. 2011 Mar;22(3):251-8 - PubMed
  11. Tissue Eng Part B Rev. 2010 Oct;16(5):493-507 - PubMed
  12. Clin Oral Implants Res. 2010 Feb;21(2):201-8 - PubMed
  13. Int J Oral Maxillofac Implants. 1999 Nov-Dec;14(6):835-40 - PubMed
  14. Tissue Eng Part B Rev. 2010 Jun;16(3):295-303 - PubMed
  15. Clin Oral Implants Res. 2008 Aug;19(8):796-803 - PubMed
  16. Crit Rev Eukaryot Gene Expr. 2000;10(3-4):259-71 - PubMed
  17. J Dent (Tehran). 2012 Summer;9(3):237-46 - PubMed
  18. Clin Orthop Relat Res. 2005 Jun;(435):62-8 - PubMed
  19. J Periodontol. 2008 Sep;79(9):1789-96 - PubMed
  20. Biol Pharm Bull. 2002 Apr;25(4):509-15 - PubMed
  21. Stem Cells. 2003;21(5):588-97 - PubMed
  22. Tissue Eng Part A. 2011 Sep;17(17-18):2187-97 - PubMed
  23. J Oral Surg. 1980 Aug;38(8):613-6 - PubMed
  24. Phys Sportsmed. 2013 Sep;41(3):7-18 - PubMed
  25. Clin Oral Implants Res. 2010 May;21(5):535-42 - PubMed
  26. Transfus Apher Sci. 2004 Apr;30(2):169-74 - PubMed
  27. Int J Oral Maxillofac Surg. 2012 Jan;41(1):114-20 - PubMed
  28. Tissue Eng Part C Methods. 2010 Apr;16(2):215-23 - PubMed
  29. Clin Oral Implants Res. 2009 Sep;20 Suppl 4:124-33 - PubMed
  30. Bone. 2012 May;50(5):1123-9 - PubMed
  31. J Periodontol. 2010 Dec;81(12):1759-64 - PubMed
  32. Int J Oral Maxillofac Implants. 2009;24 Suppl:218-36 - PubMed
  33. Clin Oral Implants Res. 2014 May;25(5):567-72 - PubMed
  34. Oman Med J. 2010 Jan;25(1):26-31 - PubMed
  35. Int J Periodontics Restorative Dent. 2004 Dec;24(6):565-77 - PubMed
  36. Clin Oral Implants Res. 2012 Aug;23(8):918-24 - PubMed
  37. J Oral Implantol. 2011 Apr;37(2):223-31 - PubMed

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