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Meillier A, Heller C. Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event. Case Rep Med. 2015;2015:217951doi: 10.1155/2015/217951.
Meillier, A., & Heller, C. (2015). Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event. Case reports in medicine, 2015217951. https://doi.org/10.1155/2015/217951
Meillier, Andrew, and Heller, Cara. "Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event." Case reports in medicine vol. 2015 (2015): 217951. doi: https://doi.org/10.1155/2015/217951
Meillier A, Heller C. Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event. Case Rep Med. 2015;2015:217951. doi: 10.1155/2015/217951. Epub 2015 Oct 12. PMID: 26543483; PMCID: PMC4620268.
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Case Rep Med. 2015;2015:217951. doi: 10.1155/2015/217951. Epub 2015 Oct 12.

Acute Cyanide Poisoning: Hydroxocobalamin and Sodium Thiosulfate Treatments with Two Outcomes following One Exposure Event.

Case reports in medicine

Andrew Meillier, Cara Heller

Affiliations

  1. Department of Medicine, Temple University Hospital, Philadelphia, PA 19140, USA.

PMID: 26543483 PMCID: PMC4620268 DOI: 10.1155/2015/217951

Abstract

Cyanide is rapidly reacting and causes arrest of aerobic metabolism. The symptoms are diffuse and lethal and require high clinical suspicion. Remediation of symptoms and mortality is highly dependent on quick treatment with a cyanide antidote. Presently, there are two widely accepted antidotes: sodium thiosulfate and hydroxocobalamin. These treatments act on different components of cyanide's metabolism. Here, we present two cases resulting from the same source of cyanide poisoning and the use of both antidotes separately used with differing outcomes.

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