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J Community Hosp Intern Med Perspect. 2015 Oct 19;5(5):28745. doi: 10.3402/jchimp.v5.28745. eCollection 2015.

Heparin-induced thrombocytopenia following coronary artery bypass grafting: a diagnostic dilemma.

Journal of community hospital internal medicine perspectives

Raju Khanal, Paras Karmacharya, Daniel A Forman

Affiliations

  1. Department of Internal Medicine, Reading Health System, West Reading, PA, USA; [email protected].
  2. Department of Internal Medicine, Reading Health System, West Reading, PA, USA.
  3. Hematology Oncology, Reading Health Physician Network, West Reading, PA, USA.

PMID: 26486110 PMCID: PMC4612479 DOI: 10.3402/jchimp.v5.28745

Abstract

The diagnosis of heparin-induced thrombocytopenia (HIT) is a challenge in post-cardiac surgery patients because of the high incidence of non-immune thrombocytopenia and heparin-platelet factor 4 antibodies in these groups. We present a case of HIT in a post coronary artery bypass surgery patient, which was successfully treated with prompt recognition and discontinuation of heparin products.

Keywords: CABG; HIT; heparin-induced thrombocytopenia; serotonin release assay

References

  1. J Thromb Haemost. 2010 Jan;8(1):30-6 - PubMed
  2. Hematology Am Soc Hematol Educ Program. 2009;:225-32 - PubMed
  3. Am Heart J. 2006 Jul;152(1):19-26 - PubMed
  4. Chest. 2012 Feb;141(2 Suppl):e495S-530S - PubMed
  5. Am J Surg. 2010 Jan;199(1):43-51 - PubMed
  6. Am J Hematol. 2007 Dec;82(12):1037-43 - PubMed
  7. Expert Rev Hematol. 2010 Oct;3(5):567-81 - PubMed
  8. J Thorac Cardiovasc Surg. 2012 May;143(5):1213-8 - PubMed
  9. Blood. 2014 Apr 17;123(16):2485-93 - PubMed
  10. Semin Thromb Hemost. 2015 Feb;41(1):49-60 - PubMed
  11. Curr Opin Anaesthesiol. 2010 Feb;23 (1):74-9 - PubMed
  12. BMJ. 2015 Jan 08;350:g7566 - PubMed
  13. J Thromb Haemost. 2008 Mar;6(3):428-35 - PubMed
  14. Ann Thorac Surg. 2003 Dec;76(6):2121-31 - PubMed
  15. Chest. 2013 Oct;144(4):1269-75 - PubMed
  16. Thromb Res. 2015 Jan;135(1):1-2 - PubMed

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