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Alp E, Orhan T, Kürkcü CA, et al. The first six years of surveillance in pediatric and neonatal intensive care units in Turkey. Antimicrob Resist Infect Control. 2015;4:34doi: 10.1186/s13756-015-0074-3.
Alp, E., Orhan, T., Kürkcü, C. A., Ersoy, S., & McLaws, M. L. (2015). The first six years of surveillance in pediatric and neonatal intensive care units in Turkey. Antimicrobial resistance and infection control, 434. https://doi.org/10.1186/s13756-015-0074-3
Alp, Emine, et al. "The first six years of surveillance in pediatric and neonatal intensive care units in Turkey." Antimicrobial resistance and infection control vol. 4 (2015): 34. doi: https://doi.org/10.1186/s13756-015-0074-3
Alp E, Orhan T, Kürkcü CA, Ersoy S, McLaws ML. The first six years of surveillance in pediatric and neonatal intensive care units in Turkey. Antimicrob Resist Infect Control. 2015 Aug 25;4:34. doi: 10.1186/s13756-015-0074-3. eCollection 2015. PMID: 26516455; PMCID: PMC4625607.
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Antimicrob Resist Infect Control. 2015 Aug 25;4:34. doi: 10.1186/s13756-015-0074-3. eCollection 2015.

The first six years of surveillance in pediatric and neonatal intensive care units in Turkey.

Antimicrobial resistance and infection control

Emine Alp, Tülay Orhan, Cemile Atalay Kürkcü, Safiye Ersoy, Mary-Louise McLaws

Affiliations

  1. Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, and Infection Control Committee, Erciyes University, Kayseri, Turkey.
  2. Faculty of Medicine, Faculty of Medicine, Infection Control Committee, Erciyes University, Kayseri, Turkey.
  3. School of Public Health and Community Medicine, UNSW Medicine, The University of New South Wales, Level 3 Samuels Building, Sydney, NSW 2052 Australia.

PMID: 26516455 PMCID: PMC4625607 DOI: 10.1186/s13756-015-0074-3

Abstract

BACKGROUND: Patients in resourced-limited neonatal and pediatric intensive care units (NICU and PICU) are vulnerable to healthcare associated infections (HAI). We report the incidence of HAI, multidrug resistant microorganisms (MDROs) and the pattern of antibiotic usage in the first six years of a surveillance program in a teaching hospital in Turkey.

METHODS: Between 2007 and 2012 surveillance data for HAI, MDROs and antibiotic usage were collected from the infection control department, pathology, hospital admissions and pharmacy. In 2009 hand hygiene auditing was introduced. Hand sanitizer usage was expressed as liters per 1000 patient-days. Antibiotic usage was presented as defined daily doses (DDD). Evidence of change in the incidence of HAI was tested using Poison regression modeling.

RESULTS: The rate of gram negative MDRO in PICU increased significant between 2007 and 2012 (IRR 1.5, P = 0.033) but remained unchanged in NICU (P = 0.824). By 2012 ceftriaxone prescribing in PICU had decreased while carbapenem prescribing increased by 80 %. In NICU carbapenem decreased by 42 % and betalactam decreased by 29 %. Hand hygiene compliance significantly improved in PICU (IRR 1.9, p < 0.001) and NICU (IRR 2.2, p < 0.001) but compliance remained modest after three years with inconsistent levels across the 5 moments.

CONCLUSION: The early years of our infection control program highlights the endemicity of HAI and MDROs in our NICU and PICU. The consistent pattern of antibiotic usage, endemic MROs in PICU and modest hand hygiene clearly provide strategic focuses for intervention.

Keywords: Antibiotic; Associated; Consumption; Healthcare; Infection; Multiple; Resistance; Surveillance

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