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Probst P, Haller S, Dörr-Harim C, et al. Nutritional Risk in Major Abdominal Surgery: Protocol of a Prospective Observational Trial to Evaluate the Prognostic Value of Different Nutritional Scores in Pancreatic Surgery. JMIR Res Protoc. 2015;4(4):e132doi: 10.2196/resprot.4567.
Probst, P., Haller, S., Dörr-Harim, C., Bruckner, T., Ulrich, A., Hackert, T., Diener, M. K., & Knebel, P. (2015). Nutritional Risk in Major Abdominal Surgery: Protocol of a Prospective Observational Trial to Evaluate the Prognostic Value of Different Nutritional Scores in Pancreatic Surgery. JMIR research protocols, 4(4), e132. https://doi.org/10.2196/resprot.4567
Probst, Pascal, et al. "Nutritional Risk in Major Abdominal Surgery: Protocol of a Prospective Observational Trial to Evaluate the Prognostic Value of Different Nutritional Scores in Pancreatic Surgery." JMIR research protocols vol. 4,4 (2015): e132. doi: https://doi.org/10.2196/resprot.4567
Probst P, Haller S, Dörr-Harim C, Bruckner T, Ulrich A, Hackert T, Diener MK, Knebel P. Nutritional Risk in Major Abdominal Surgery: Protocol of a Prospective Observational Trial to Evaluate the Prognostic Value of Different Nutritional Scores in Pancreatic Surgery. JMIR Res Protoc. 2015 Nov 16;4(4):e132. doi: 10.2196/resprot.4567. PMID: 26573991; PMCID: PMC4704883.
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JMIR Res Protoc. 2015 Nov 16;4(4):e132. doi: 10.2196/resprot.4567.

Nutritional Risk in Major Abdominal Surgery: Protocol of a Prospective Observational Trial to Evaluate the Prognostic Value of Different Nutritional Scores in Pancreatic Surgery.

JMIR research protocols

Pascal Probst, Sebastian Haller, Colette Dörr-Harim, Thomas Bruckner, Alexis Ulrich, Thilo Hackert, Markus K Diener, Phillip Knebel

Affiliations

  1. University of Heidelberg, Department of General, Visceral and Transplantation Surgery, Heidelberg, Germany.

PMID: 26573991 PMCID: PMC4704883 DOI: 10.2196/resprot.4567

Abstract

BACKGROUND: The influence of patients' preoperative nutritional status on their clinical outcome has already been proven. Therefore, patients with malnutrition are in need of additional therapeutic efforts. However, for pancreatic surgery, evidence suggesting the adequacy of existing nutritional assessment scores to estimate malnutrition associated with postoperative outcome is limited.

OBJECTIVE: The aim of the observational trial "Nutritional Risk in Major Abdominal Surgery (NURIMAS) Pancreas" is to prospectively assess and analyze different nutritional assessment scores for their prognostic value on postoperative complications in patients undergoing pancreatic surgery.

METHODS: All patients scheduled to receive elective pancreatic surgery at the University Hospital of Heidelberg will be screened for eligibility. Preoperatively, 12 nutritional assessment scores will be collected and patients will be assigned either at risk or not at risk for malnutrition. The postoperative course will be followed prospectively and complications according to the Clavien-Dindo classification will be recorded. The prognostic value for complications will be evaluated for every score in a univariable and multivariable analysis corrected for known risk factors in pancreatic surgery.

RESULTS: Final data analysis is expected to be available during Spring 2016.

CONCLUSIONS: The NURIMAS Pancreas trial is a monocentric, prospective, observational trial aiming to find the most predictive clinical nutritional assessment score for postoperative complications. Using the results of this protocol as a knowledge base, it is possible to conduct nutritional risk-guided intervention trials to prevent postoperative complications in the pancreatic surgical population.

TRIAL REGISTRATION: germanctr.de: DRKS00006340; https://drks-neu.uniklinik-freiburg.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00006340 (Archived by WebCite at http://www.webcitation.org/6bzXWSRYZ).

Keywords: Diagnosis Related Group system; malnutrition; nutritional assessment; nutritional score; pancreatic surgery

References

  1. Clin Nutr. 2014 Feb;33(1):39-58 - PubMed
  2. Clin Nutr. 2015 Jun;34(3):335-40 - PubMed
  3. Eur J Cancer. 1998 Mar;34(4):503-9 - PubMed
  4. J Surg Oncol. 2013 Jun;107(7):702-8 - PubMed
  5. N Engl J Med. 1991 Aug 22;325(8):525-32 - PubMed
  6. Ann Intern Med. 2013 Feb 5;158(3):200-7 - PubMed
  7. Clin Nutr. 1995 Oct;14(5):269-73 - PubMed
  8. Surg Today. 2013 Mar;43(3):276-83 - PubMed
  9. Clin Nutr. 1999 Jun;18(3):141-7 - PubMed
  10. Clin Nutr. 2003 Aug;22(4):415-21 - PubMed
  11. Clin Nutr. 2008 Aug;27(4):565-70 - PubMed
  12. Ann Surg. 2014 Nov;260(5):757-62; discussion 762-3 - PubMed
  13. Intensive Care Med. 2013 Feb;39(2):165-228 - PubMed
  14. J Hepatobiliary Pancreat Sci. 2011 Jul;18(4):601-8 - PubMed
  15. Ann Intern Med. 2003 Jan 7;138(1):40-4 - PubMed
  16. Nutr Clin Pract. 1997 Feb;12(1):20-5 - PubMed
  17. Clin Nutr. 2003 Oct;22(5):473-81 - PubMed
  18. Lancet. 2012 Dec 15;380(9859):2197-223 - PubMed
  19. J Hum Nutr Diet. 2009 Dec;22(6):536-44 - PubMed
  20. Surgery. 2009 May;145(5):519-26 - PubMed
  21. J Am Coll Surg. 2013 Jan;216(1):1-14 - PubMed
  22. J Am Coll Surg. 2008 Nov;207(5):751-7 - PubMed
  23. Am J Clin Nutr. 1998 Aug;68(2):275-81 - PubMed
  24. World J Surg. 2006 Mar;30(3):378-90 - PubMed
  25. Surgery. 2011 May;149(5):680-8 - PubMed
  26. Stat Methods Med Res. 1999 Mar;8(1):3-15 - PubMed
  27. Arch Med Res. 1995 Spring;26(1):31-4 - PubMed
  28. Nutrition. 1996 Jan;12(1):23-9 - PubMed
  29. JAMA. 2013 Nov 27;310(20):2191-4 - PubMed
  30. Ann Surg. 2004 Aug;240(2):205-13 - PubMed
  31. Surgery. 2007 Jul;142(1):20-5 - PubMed
  32. Infect Control Hosp Epidemiol. 1992 Oct;13(10):606-8 - PubMed
  33. J Gerontol A Biol Sci Med Sci. 2001 Jun;56(6):M366-72 - PubMed
  34. Am J Med. 1980 May;68(5):683-90 - PubMed
  35. JAMA. 1974 Nov 11;230(6):858-60 - PubMed
  36. Surgery. 2005 Jul;138(1):8-13 - PubMed
  37. JAMA. 1976 Apr 12;235(15):1567-70 - PubMed
  38. Emerg Med J. 2005 Mar;22(3):180-1 - PubMed
  39. J Am Coll Nutr. 2004 Jun;23(3):227-32 - PubMed
  40. Surgery. 2007 Nov;142(5):761-8 - PubMed
  41. Nutr Hosp. 2008 Jul-Aug;23(4):400-7 - PubMed
  42. Clin Nutr. 2005 Feb;24(1):75-82 - PubMed

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