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Jun HO, Yu JJ, Kang SY, et al. Diagnostic characteristics of supplemental laboratory criteria for incomplete Kawasaki disease in children with complete Kawasaki disease. Korean J Pediatr. 2015;58(10):369-73doi: 10.3345/kjp.2015.58.10.369.
Jun, H. O., Yu, J. J., Kang, S. Y., Seo, C. D., Baek, J. S., Kim, Y. H., & Ko, J. K. (2015). Diagnostic characteristics of supplemental laboratory criteria for incomplete Kawasaki disease in children with complete Kawasaki disease. Korean journal of pediatrics, 58(10), 369-73. https://doi.org/10.3345/kjp.2015.58.10.369
Jun, Hyun Ok, et al. "Diagnostic characteristics of supplemental laboratory criteria for incomplete Kawasaki disease in children with complete Kawasaki disease." Korean journal of pediatrics vol. 58,10 (2015): 369-73. doi: https://doi.org/10.3345/kjp.2015.58.10.369
Jun HO, Yu JJ, Kang SY, Seo CD, Baek JS, Kim YH, Ko JK. Diagnostic characteristics of supplemental laboratory criteria for incomplete Kawasaki disease in children with complete Kawasaki disease. Korean J Pediatr. 2015 Oct;58(10):369-73. doi: 10.3345/kjp.2015.58.10.369. Epub 2015 Oct 21. PMID: 26576180; PMCID: PMC4644764.
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Korean J Pediatr. 2015 Oct;58(10):369-73. doi: 10.3345/kjp.2015.58.10.369. Epub 2015 Oct 21.

Diagnostic characteristics of supplemental laboratory criteria for incomplete Kawasaki disease in children with complete Kawasaki disease.

Korean journal of pediatrics

Hyun Ok Jun, Jeong Jin Yu, So Yeon Kang, Chang Deok Seo, Jae Suk Baek, Young-Hwue Kim, Jae-Kon Ko

Affiliations

  1. Department of Pediatrics, University of Ulsan College of Medicine, Seoul, Korea.

PMID: 26576180 PMCID: PMC4644764 DOI: 10.3345/kjp.2015.58.10.369

Abstract

PURPOSE: In 2004, the American Heart Association (AHA) had published an algorithm for the diagnosis of incomplete Kawasaki disease (KD). The aim of the present study was to investigate characteristics of supplemental laboratory criteria in this algorithm.

METHODS: We retrospectively examined the medical records of 355 patients with KD who were treated with intravenous immunoglobulin (IVIG) during the acute phase of the disease. Laboratory data were obtained before the initial IVIG administration and up to 10 days after fever onset. In 106 patients, laboratory testing was performed more than twice.

RESULTS: The AHA supplemental laboratory criteria were fulfilled in 90 patients (25.4%), and the frequency of laboratory examination (odds ratio [OR], 1.981; 95% confidence interval [CI], 1.391-2.821; P<0.001) was a significant predictor of it. The fulfillment of AHA supplemental laboratory criteria was significantly associated with refractoriness to the initial IVIG administration (OR, 2.388; 95% CI, 1.182-4.826; P=0.013) and dilatation of coronary arteries (OR, 2.776; 95% CI, 1.519-5.074; P=0.001).

CONCLUSION: Repeated laboratory testing increased the rate of fulfillment of the AHA supplemental laboratory criteria in children with KD.

Keywords: Diagnosis of Kawasaki disease; Incomplete Kawasaki disease; Kawasaki disease; Laboratory examinations

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