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Kousoulaki K, Østbye TK, Krasnov A, et al. Metabolism, health and fillet nutritional quality in Atlantic salmon (Salmo salar) fed diets containing n-3-rich microalgae. J Nutr Sci. 2015;4:e24doi: 10.1017/jns.2015.14.
Kousoulaki, K., Østbye, T. K., Krasnov, A., Torgersen, J. S., Mørkøre, T., & Sweetman, J. (2015). Metabolism, health and fillet nutritional quality in Atlantic salmon (Salmo salar) fed diets containing n-3-rich microalgae. Journal of nutritional science, 4e24. https://doi.org/10.1017/jns.2015.14
Kousoulaki, Katerina, et al. "Metabolism, health and fillet nutritional quality in Atlantic salmon (Salmo salar) fed diets containing n-3-rich microalgae." Journal of nutritional science vol. 4 (2015): e24. doi: https://doi.org/10.1017/jns.2015.14
Kousoulaki K, Østbye TK, Krasnov A, Torgersen JS, Mørkøre T, Sweetman J. Metabolism, health and fillet nutritional quality in Atlantic salmon (Salmo salar) fed diets containing n-3-rich microalgae. J Nutr Sci. 2015 Jun 11;4:e24. doi: 10.1017/jns.2015.14. eCollection 2015. PMID: 26495116; PMCID: PMC4611082.
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J Nutr Sci. 2015 Jun 11;4:e24. doi: 10.1017/jns.2015.14. eCollection 2015.

Metabolism, health and fillet nutritional quality in Atlantic salmon (Salmo salar) fed diets containing n-3-rich microalgae.

Journal of nutritional science

Katerina Kousoulaki, Tone-Kari Knutsdatter Østbye, Aleksei Krasnov, Jacob Seilø Torgersen, Turid Mørkøre, John Sweetman

Affiliations

  1. Nofima AS , Department of Nutrition and Feed Technology , N-5141 Fyllingsdalen , Norway.
  2. Alltech Inc. , Sarney , Dunboyne , County Meath , Republic of Ireland.

PMID: 26495116 PMCID: PMC4611082 DOI: 10.1017/jns.2015.14

Abstract

Microalgae, as primary producers of EPA and DHA, are among the most prominent alternative sources to fish oil for n-3 long-chain PUFA in animal and human nutrition. The present study aimed to assess technical, nutritional and fish health aspects of producing n-3-rich Atlantic salmon (Salmo salar) fish fillets by dietary supplementation of increasing levels of a DHA-producing Schizochytrium sp. and reduced or without use of supplemental fish oil. Atlantic salmon smolt were fed diets with graded levels of microalgae for 12 weeks, during which all fish showed high feed intake rates with postprandial plasma leptin levels inversely correlating with final mean fish body weights. Fish performance was optimal in all experimental treatments (thermal growth coefficient about 4·0 and feed conversion ratio 0·8-0·9), protein digestibility was equal in all diets, whereas dietary lipid digestibility inversely correlated with the dietary levels of the SFA 16 : 0. Fillet quality was good and similar to the control in all treatments in terms of n-3 long-chain PUFA content, gaping, texture and liquid losses during thawing. Histological fluorescence staining and immunofluorescence analysis of salmon intestines (midgut: base of intestine and villi) revealed significant effects on slime, goblet cell production and inducible nitric oxide synthase (iNOS) activity with increasing levels of dietary Schizochytrium sp. supplementation. Microarray analysis did not reveal any signs of toxicity, stress, inflammation or any other negative effects from Schizochytrium sp. supplementation in diets for Atlantic salmon.

Keywords: 0_ScYE, 0 g/kg Scizochytrium sp. + yeast extract (control); 15_ScYE, 150 g/kg Scizochytrium sp. + yeast extract; 1_ScYE, 10 g/kg Scizochytrium sp. + yeast extract; 6_ScYE, 60 g/kg Scizochytrium sp. + yeast extract; ADC, apparent digestibility coefficient; CK, creatine kinase; FAME, fatty acid methyl esters; FCR, feed conversion ratio; Farmed salmon fish fillet nutritional quality; ISO, International Organization for Standardization; Microalgae; ScYE, Scizochytrium sp. + yeast extract; TGC, thermal growth coefficient; iNOS, inducible nitric oxide synthase; n-3 LC-PUFA, n-3 long-chain PUFA; n-3 Long-chain PUFA

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