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Verma A, Kumar N, Malviya R, et al. Emerging Trends in Noninvasive Insulin Delivery. J Pharm (Cairo). 2014;2014:378048doi: 10.1155/2014/378048.
Verma, A., Kumar, N., Malviya, R., & Sharma, P. K. (2014). Emerging Trends in Noninvasive Insulin Delivery. Journal of pharmaceutics, 2014378048. https://doi.org/10.1155/2014/378048
Verma, Arun, et al. "Emerging Trends in Noninvasive Insulin Delivery." Journal of pharmaceutics vol. 2014 (2014): 378048. doi: https://doi.org/10.1155/2014/378048
Verma A, Kumar N, Malviya R, Sharma PK. Emerging Trends in Noninvasive Insulin Delivery. J Pharm (Cairo). 2014;2014:378048. doi: 10.1155/2014/378048. Epub 2014 May 14. PMID: 26556194; PMCID: PMC4590826.
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J Pharm (Cairo). 2014;2014:378048. doi: 10.1155/2014/378048. Epub 2014 May 14.

Emerging Trends in Noninvasive Insulin Delivery.

Journal of pharmaceutics

Arun Verma, Nitin Kumar, Rishabha Malviya, Pramod Kumar Sharma

Affiliations

  1. Department of Pharmacy, School of Medical & Allied Sciences, Galgotias University, Yamuna Expressway, Greater Noida, Uttar Pradesh, India.

PMID: 26556194 PMCID: PMC4590826 DOI: 10.1155/2014/378048

Abstract

This paper deals with various aspects of oral insulin delivery system. Insulin is used for the treatment of diabetes mellitus, which is characterized by the elevated glucose level (above the normal range) in the blood stream, that is, hyperglycemia. Oral route of administration of any drug is the most convenient route. Development of oral insulin is still under research. Oral insulin will cause the avoidance of pain during the injection (in subcutaneous administration), anxiety due to needle, and infections which can be developed. Different types of enzyme inhibitors, like sodium cholate, camostat, mesilate, bacitracin, leupeptin, and so forth, have been used to prevent insulin from enzymatic degradation. Subcutaneous route has been used for administration of insulin, but pain and itching at the site of administration can occur. That is why various alternative routes of insulin administration like oral route are under investigation. In this paper authors summarized advancement in insulin delivery with their formulation aspects.

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