Display options
Cite
Nag S, Sarkar S, Chattopadhyay D, et al. Seroprevalence of Herpes Simplex Virus Infection in HIV Coinfected Individuals in Eastern India with Risk Factor Analysis. Adv Virol. 2015;2015:537939doi: 10.1155/2015/537939.
Nag, S., Sarkar, S., Chattopadhyay, D., Bhattacharya, S., Biswas, R., & SenGupta, M. (2015). Seroprevalence of Herpes Simplex Virus Infection in HIV Coinfected Individuals in Eastern India with Risk Factor Analysis. Advances in virology, 2015537939. https://doi.org/10.1155/2015/537939
Nag, Soumyabrata, et al. "Seroprevalence of Herpes Simplex Virus Infection in HIV Coinfected Individuals in Eastern India with Risk Factor Analysis." Advances in virology vol. 2015 (2015): 537939. doi: https://doi.org/10.1155/2015/537939
Nag S, Sarkar S, Chattopadhyay D, Bhattacharya S, Biswas R, SenGupta M. Seroprevalence of Herpes Simplex Virus Infection in HIV Coinfected Individuals in Eastern India with Risk Factor Analysis. Adv Virol. 2015;2015:537939. doi: 10.1155/2015/537939. Epub 2015 Oct 19. PMID: 26557849; PMCID: PMC4628955.
Copy Download .nbib Format: NLM
Share it on

Adv Virol. 2015;2015:537939. doi: 10.1155/2015/537939. Epub 2015 Oct 19.

Seroprevalence of Herpes Simplex Virus Infection in HIV Coinfected Individuals in Eastern India with Risk Factor Analysis.

Advances in virology

Soumyabrata Nag, Soma Sarkar, Debprasad Chattopadhyay, Sanjoy Bhattacharya, Rahul Biswas, Manideepa SenGupta

Affiliations

  1. Department of Microbiology, IIMSAR & BCRH, Haldia, West Bengal, India.
  2. Department of Microbiology, Medical College Kolkata, 88 College Street, Kolkata, West Bengal, India.
  3. ICMR Virus Unit, I.D. and B.G. Hospital, GB-4, 1st Floor, 57 Dr. S. C. Banerjee Road, Beliaghata, Kolkata, India.
  4. Department of Medicine, Medical College Kolkata, 88 College Street, Kolkata, West Bengal, India.
  5. Department of Community Medicine, A.I.I.H. & P.H., Kolkata, West Bengal, India.

PMID: 26557849 PMCID: PMC4628955 DOI: 10.1155/2015/537939

Abstract

Herpes simplex virus type 2 (HSV-2) is the cause of most genital herpes while HSV-1 is responsible for orolabial and facial lesions. In immunocompromised individuals, like HIV patients, impaired immunity leads to more frequent symptomatic and asymptomatic HSV infection. Fifty-two blood samples from HIV patients with clinically diagnosed HSV infection were taken as cases, while 45 blood samples each from HIV-infected (HIV control) and noninfected patients without any herpetic lesion (non-HIV control) were taken as control. Serum was tested for IgM and IgG antibodies of both HSV-1 and HSV-2 by ELISA. The seroprevalence was compared among the three groups of study population, considering the demographic and socioeconomic parameters. The HSV-2 IgM was significantly higher (p < 0.005) in the HIV patient group (34.6%) than the HIV control (2.2%) and non-HIV control (2.2%) groups, whereas HSV-2 IgG seroprevalence was higher in both HIV patient (61.5%) and HIV control (57.8%) groups than the non-HIV control group (17.8%). The prevalence of HSV-2 was significantly higher in persons with multiple partners and in the reproductive age group. The overall seroprevalence of HSV-1 IgM was too low (<5%), whereas it was too high (about 90%) with HSV-1 IgG in all three study groups.

References

  1. J Clin Virol. 2001 Oct;22(3):305-13 - PubMed
  2. J Infect Dis. 1992 Aug;166(2):418-20 - PubMed
  3. JAMA. 2006 Aug 23;296(8):964-73 - PubMed
  4. J Infect Dis. 1992 Feb;165(2):251-5 - PubMed
  5. J Infect Dis. 2000 Oct;182(4):1090-6 - PubMed
  6. JAMA. 2000 Feb 9;283(6):791-4 - PubMed
  7. AIDS. 1991 Sep;5(9):1107-10 - PubMed
  8. J Infect Dis. 2002 Jan 1;185(1):45-52 - PubMed
  9. Coll Antropol. 2008 Sep;32(3):693-5 - PubMed
  10. J Infect Dev Ctries. 2010 Oct 04;4(9):572-5 - PubMed
  11. Sex Transm Dis. 2012 Feb;39(2):154-60 - PubMed
  12. Sex Transm Dis. 1992 Mar-Apr;19(2):61-77 - PubMed
  13. J Med Virol. 2000 Jun;61(2):201-7 - PubMed
  14. Int J Dermatol. 2011 Jun;50(6):709-13 - PubMed
  15. N Engl J Med. 2004 May 6;350(19):1970-7 - PubMed
  16. Sex Transm Infect. 2003 Aug;79(4):286-90 - PubMed

Publication Types