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da Conceição AV, Bernardo D, Lopes LV, et al. Oncology pharmacy units: a safety policy for handling hazardous drugs and related waste in low- and middle-income African countries-Angolan experience. Ecancermedicalscience. 2015;9:575doi: 10.3332/ecancer.2015.575.
da Conceição, A. V., Bernardo, D., Lopes, L. V., Miguel, F., Bessa, F., Monteiro, F., Santos, C., Oliveira, B., & Santos, L. L. (2015). Oncology pharmacy units: a safety policy for handling hazardous drugs and related waste in low- and middle-income African countries-Angolan experience. Ecancermedicalscience, 9575. https://doi.org/10.3332/ecancer.2015.575
da Conceição, Ana Vaz, et al. "Oncology pharmacy units: a safety policy for handling hazardous drugs and related waste in low- and middle-income African countries-Angolan experience." Ecancermedicalscience vol. 9 (2015): 575. doi: https://doi.org/10.3332/ecancer.2015.575
da Conceição AV, Bernardo D, Lopes LV, Miguel F, Bessa F, Monteiro F, Santos C, Oliveira B, Santos LL. Oncology pharmacy units: a safety policy for handling hazardous drugs and related waste in low- and middle-income African countries-Angolan experience. Ecancermedicalscience. 2015 Oct 01;9:575. doi: 10.3332/ecancer.2015.575. eCollection 2015. PMID: 26557873; PMCID: PMC4631569.
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Ecancermedicalscience. 2015 Oct 01;9:575. doi: 10.3332/ecancer.2015.575. eCollection 2015.

Oncology pharmacy units: a safety policy for handling hazardous drugs and related waste in low- and middle-income African countries-Angolan experience.

Ecancermedicalscience

Ana Vaz da Conceição, Dora Bernardo, Lygia Vieira Lopes, Fernando Miguel, Fernanda Bessa, Fernando Monteiro, Cristina Santos, Blasques Oliveira, Lúcio Lara Santos

Affiliations

  1. Cancer Unit of Girassol Clinic, Comandante Gika 225, Luanda, Angola.
  2. Pharmacy Department of Portuguese Institute of Oncology, Rua Dr António Bernardino de Almeida - 4200-072, Porto, Portugal.
  3. Cancer Unit of Sagrada Esperança Clinic, Av Murtala Mohammed, Luanda, Angola.
  4. Angolan Institute of Cancer Control, Rua Amilcar Cabral, Luanda, Angola.
  5. Nurse Department of Portuguese Institute of Oncology, Rua Dr António Bernardino de Almeida - 4200-072, Porto, Portugal.
  6. ONCOCIR - Education and Care in Oncology, Marçal, Luanda, Angola.
  7. ONCOCIR - Education and Care in Oncology, Marçal, Luanda, Angola ; Experimental Pathology and Therapeutics Group and Surgical Oncology Department, Portuguese Institute of Oncology, Rua Dr António Bernardino de Almeida - 4200-072, Porto, Portugal.

PMID: 26557873 PMCID: PMC4631569 DOI: 10.3332/ecancer.2015.575

Abstract

In African countries, higher rates of late-stage cancers at the time of first diagnosis are a reality. In this context, hazardous drugs (HDs), such as chemotherapy, play an important role and have immense benefits for patients' treatment. HDs should be handled under specific conditions. At least a class 5 environment primary engineering control (PEC), physically located in an appropriate buffer area, is mandatory for sterile HDs compounding, as well as administrative control, personal protective equipment, work practices and other engineering and environmental controls, in order to protect the environment, patient, and worker. The aim of this study is to describe the Angolan experience regarding the development of oncology pharmacy units and discuss international evidence-based guidelines on handling HDs and related waste. Measures to incorporate modern and economical solutions to upgrade or build adequate and safe facilities and staff training, in order to comply with international guidelines in this area, are crucial tasks for African countries of low and middle income.

Keywords: Angola; chemotherapy; hazardous drugs; low- and middle-income industries; oncology pharmacy units

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