Display options
Cite
Soliman SA, Shokeir AA, El-Hefnawy AS, et al. Vascular and haemorrhagic complications of adult and paediatric live-donor renal transplantation: A single-centre study with a long-term follow-up. Arab J Urol. 2012;10(2):155-61doi: 10.1016/j.aju.2011.12.002.
Soliman, S. A., Shokeir, A. A., El-Hefnawy, A. S., Harraz, A. M., Kamal, M. M., Shehab El-Din, A. B., & Ghoneim, M. A. (2012). Vascular and haemorrhagic complications of adult and paediatric live-donor renal transplantation: A single-centre study with a long-term follow-up. Arab journal of urology, 10(2), 155-61. https://doi.org/10.1016/j.aju.2011.12.002
Soliman, Shady A, et al. "Vascular and haemorrhagic complications of adult and paediatric live-donor renal transplantation: A single-centre study with a long-term follow-up." Arab journal of urology vol. 10,2 (2012): 155-61. doi: https://doi.org/10.1016/j.aju.2011.12.002
Soliman SA, Shokeir AA, El-Hefnawy AS, Harraz AM, Kamal MM, Shehab El-Din AB, Ghoneim MA. Vascular and haemorrhagic complications of adult and paediatric live-donor renal transplantation: A single-centre study with a long-term follow-up. Arab J Urol. 2012 Jun;10(2):155-61. doi: 10.1016/j.aju.2011.12.002. Epub 2012 Jan 30. PMID: 26558019; PMCID: PMC4442900.
Copy Download .nbib Format: NLM
Share it on

Arab J Urol. 2012 Jun;10(2):155-61. doi: 10.1016/j.aju.2011.12.002. Epub 2012 Jan 30.

Vascular and haemorrhagic complications of adult and paediatric live-donor renal transplantation: A single-centre study with a long-term follow-up.

Arab journal of urology

Shady A Soliman, Ahmed A Shokeir, Ahmed S El-Hefnawy, Ahmed M Harraz, Mohamed M Kamal, Ahmed B Shehab El-Din, Mohamed A Ghoneim

Affiliations

  1. Urology & Nephrology Center, Mansoura University, Mansoura, Egypt.

PMID: 26558019 PMCID: PMC4442900 DOI: 10.1016/j.aju.2011.12.002

Abstract

OBJECTIVES: To compare the haemorrhagic and vascular complications between paediatric and adult renal transplant recipients with a long-term follow-up.

PATIENTS AND METHODS: Between March 1976 and December 2006, in all, 1865 live-donor renal transplants were carried out. Patients were stratified according to their ages into two groups; paediatric (⩽18 years; 259) and adult (>18 years; 1606). Variables assessed included incidence, risk factors, management and sequelae of vascular and haemorrhagic complications. The effect of these complications on patient and graft survival was compared.

RESULTS: Haemorrhage requiring active intervention (percutaneous drainage or surgical exploration) was reported in seven children (2.7%) and 29 adults (1.8%), while thrombotic or stenotic complications were recorded in two children (0.77%) and 19 adults (1.18%; P < 0.05). Female gender, delayed onset of diuresis and acute tubular necrosis were significant predictors of vascular complications on univariate analysis, but none remained significant on multivariate analysis. In adults, vascular complications had a significant negative effect on mean (SD) 10-year graft survival compared to patients with no complications, at 19.8 (7.63)% vs. 55.7 (1.66)% (P = 0.01). Children who developed vascular complications had a significantly higher 5- and 10-year graft survival rate than adults (P = 0.01).

CONCLUSION: The incidence of vascular complications is comparable in paediatric and adult transplants. Vascular complications had a significant negative influence on graft survival in adult recipients. Children who developed vascular complications appear to tolerate its effects and have a better graft survival than have adults.

Keywords: (T)RAS, (transplant) renal artery stenosis; ATN, acute tubular necrosis; PTA, percutaneous transluminal angioplasty; Renal transplantation; US, ultrasonography; Vascular complication

References

  1. Kidney Int. 2002 Oct;62(4):1454-60 - PubMed
  2. Transplantation. 1998 Aug 27;66(4):533-4 - PubMed
  3. Transplant Proc. 2005 Mar;37(2):675-8 - PubMed
  4. J Urol. 2003 Mar;169(3):859-62 - PubMed
  5. J Pediatr Surg. 1992 May;27(5):629-33 - PubMed
  6. Clin Nephrol. 2009 May;71(5):543-9 - PubMed
  7. Arab J Urol. 2011 Sep;9(3):171-7 - PubMed
  8. Pediatr Transplant. 2010 Jun;14(4):512-9 - PubMed
  9. Nephrol Dial Transplant. 2004 Jul;19 Suppl 4:iv48-54 - PubMed
  10. Transplant Proc. 2009 Jun;41(5):1609-14 - PubMed
  11. Transplantation. 1998 Jan 27;65(2):229-34 - PubMed
  12. Int Urol Nephrol. 2008;40(4):869-73 - PubMed
  13. Transplantation. 1989 Nov;48(5):886-7 - PubMed
  14. J Cardiovasc Surg (Torino). 2008 Oct;49(5):565-70 - PubMed
  15. Transplantation. 1997 Nov 27;64(10):1424-8 - PubMed
  16. Transplantation. 1989 Oct;48(4):580-3 - PubMed
  17. J Urol. 1994 Dec;152(6 Pt 1):2055-6 - PubMed
  18. Nephrol Dial Transplant. 1992;7(3):256-9 - PubMed
  19. Ups J Med Sci. 2002;107(1):9-15 - PubMed
  20. Am J Nephrol. 2009;30(5):459-67 - PubMed
  21. J Urol. 1996 Jun;155(6):1860-4 - PubMed
  22. Am J Kidney Dis. 1998 Jan;31(1):142-8 - PubMed
  23. Nephrol Dial Transplant. 1996 Jan;11(1):140-7 - PubMed
  24. Urology. 2007 Apr;69(4):647-51 - PubMed

Publication Types