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Demir R, Saritemur M, Atis O, et al. Can we distinguish stroke and stroke mimics via red cell distribution width in young patients?. Arch Med Sci. 2015;11(5):958-63doi: 10.5114/aoms.2014.40995.
Demir, R., Saritemur, M., Atis, O., Ozel, L., Kocaturk, �. �., Emet, M., & Ulvi, H. (2015). Can we distinguish stroke and stroke mimics via red cell distribution width in young patients?. Archives of medical science : AMS, 11(5), 958-63. https://doi.org/10.5114/aoms.2014.40995
Demir, Recep, et al. "Can we distinguish stroke and stroke mimics via red cell distribution width in young patients?." Archives of medical science : AMS vol. 11,5 (2015): 958-63. doi: https://doi.org/10.5114/aoms.2014.40995
Demir R, Saritemur M, Atis O, Ozel L, Kocaturk İ, Emet M, Ulvi H. Can we distinguish stroke and stroke mimics via red cell distribution width in young patients?. Arch Med Sci. 2015 Oct 12;11(5):958-63. doi: 10.5114/aoms.2014.40995. PMID: 26528336; PMCID: PMC4624731.
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Arch Med Sci. 2015 Oct 12;11(5):958-63. doi: 10.5114/aoms.2014.40995.

Can we distinguish stroke and stroke mimics via red cell distribution width in young patients?.

Archives of medical science : AMS

Recep Demir, Murat Saritemur, Omer Atis, Lutfi Ozel, İdris Kocaturk, Mucahit Emet, Hizir Ulvi

Affiliations

  1. Department of Neurology, Medical School, Atatürk University, Erzurum, Turkey.
  2. Department of Emergency Medicine, Medical School, Atatürk University, Erzurum, Turkey.
  3. Department of Medical Biology, Medical School, Atatürk University, Erzurum, Turkey.

PMID: 26528336 PMCID: PMC4624731 DOI: 10.5114/aoms.2014.40995

Abstract

INTRODUCTION: Discrimination of stroke and stroke mimics is problematic in young patients. The aim of the study was to determine whether arterial ischemic stroke and stroke mimics can be differentiated via the red cell distribution width (RDW) value in young patients.

MATERIAL AND METHODS: In this retrospective cross-sectional study, a total of 236 patients hospitalized at the neurology ward were investigated. The patients were divided into 3 groups: the 1(st) group included young stroke patients, the 2(nd) group included patients with epilepsy, and the 3rd group included patients with multiple sclerosis (MS). Complete blood count and computed tomographic brain imaging tests were performed in all patients, and magnetic resonance imaging was done when necessary.

RESULTS: A total of 236 patients were included in this study. Ninety-five (40%) patients were young stroke patients, 71 (30%) had epilepsy and 70 (30%) had MS. The mean RDW values of young patients with stroke were significantly higher than patients with epilepsy or MS (14.9 ±1.2, 13.3 ±1.2, 13.4 ±0.6, p < 0.0001, respectively). The diagnostic power of RDW in the differentiation of patients with stroke is good (area under the curve (AUC) = 0.89). When an RDW cut-off value of 14.05% is accepted for differentiating young patients with stroke from other disorders, the sensitivity, specificity, positive predictive and negative predictive values were 73.7%, 87.9%, 6.1 and 0.043, respectively.

CONCLUSIONS: Red cell distribution width is a promising, rapid, easy and inexpensive parameter to distinguish young stroke from stroke mimics (such as epilepsy and MS) in young patients.

Keywords: diagnosis; epilepsy; multiple sclerosis; red cell distribution width; stroke

References

  1. J Neurol Sci. 2007 Jan 31;252(2):154-8 - PubMed
  2. J Neurol Sci. 2009 Feb 15;277(1-2):103-8 - PubMed
  3. Clin Appl Thromb Hemost. 2015 May;21(4):354-8 - PubMed
  4. Lancet Neurol. 2011 Nov;10(11):978-86 - PubMed
  5. Neurology. 1999 Jun 10;52(9):1784-92 - PubMed
  6. J R Coll Physicians Edinb. 2012;42(3):199-204 - PubMed
  7. Lancet Neurol. 2010 Nov;9(11):1085-96 - PubMed
  8. Radiology. 2002 Aug;224(2):353-60 - PubMed
  9. Aust Fam Physician. 2006 Oct;35(10):805-8 - PubMed
  10. BMC Neurol. 2011 Sep 20;11:109 - PubMed
  11. Eur Neurol. 2007;57(4):212-8 - PubMed
  12. J Fam Pract. 2005 Jun;54(6):536, 538-9 - PubMed
  13. JAMA. 2013 Mar 20;309(11):1136-44 - PubMed
  14. Clin Biochem. 2012 Nov;45(16-17):1302-7 - PubMed
  15. Coron Artery Dis. 2011 May;22(3):138-44 - PubMed
  16. Thromb Haemost. 2012 Aug;108(2):349-56 - PubMed
  17. Radiographics. 2006 Oct;26 Suppl 1:S75-95 - PubMed
  18. Lancet. 1982 Feb 6;1(8267):328-31 - PubMed
  19. J Stroke Cerebrovasc Dis. 2013 Nov;22(8):e397-403 - PubMed
  20. J Am Coll Cardiol. 2007 Jul 3;50(1):40-7 - PubMed
  21. Cerebrovasc Dis. 2009;27(3):295-302 - PubMed
  22. Neurocrit Care. 2011 Aug;15(1):76-9 - PubMed
  23. Eur J Phys Rehabil Med. 2011 Mar;47(1):19-23 - PubMed
  24. Emerg Med Clin North Am. 2012 Aug;30(3):795-804 - PubMed
  25. Arch Med Sci. 2015 Jun 19;11(3):530-5 - PubMed
  26. Circulation. 2004 Jul 6;110(1):46-50 - PubMed
  27. Arch Med Sci. 2012 May 9;8(2):371-4 - PubMed

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