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Lee YK, Lyu ES, Oh SY, et al. Daily Copper and Manganese Intakes and Their Relation to Blood Pressure in Normotensive Adults. Clin Nutr Res. 2015;4(4):259-66doi: 10.7762/cnr.2015.4.4.259.
Lee, Y. K., Lyu, E. S., Oh, S. Y., Park, H. R., Ro, H. K., Heo, Y. R., Hyun, T., & Choi, M. K. (2015). Daily Copper and Manganese Intakes and Their Relation to Blood Pressure in Normotensive Adults. Clinical nutrition research, 4(4), 259-66. https://doi.org/10.7762/cnr.2015.4.4.259
Lee, Yeon-Kyung, et al. "Daily Copper and Manganese Intakes and Their Relation to Blood Pressure in Normotensive Adults." Clinical nutrition research vol. 4,4 (2015): 259-66. doi: https://doi.org/10.7762/cnr.2015.4.4.259
Lee YK, Lyu ES, Oh SY, Park HR, Ro HK, Heo YR, Hyun T, Choi MK. Daily Copper and Manganese Intakes and Their Relation to Blood Pressure in Normotensive Adults. Clin Nutr Res. 2015 Oct;4(4):259-66. doi: 10.7762/cnr.2015.4.4.259. Epub 2015 Oct 31. PMID: 26566521; PMCID: PMC4641988.
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Clin Nutr Res. 2015 Oct;4(4):259-66. doi: 10.7762/cnr.2015.4.4.259. Epub 2015 Oct 31.

Daily Copper and Manganese Intakes and Their Relation to Blood Pressure in Normotensive Adults.

Clinical nutrition research

Yeon-Kyung Lee, Eun-Soon Lyu, Se-Young Oh, Hae-Ryun Park, Hee-Kyong Ro, Young-Ran Heo, Taisun Hyun, Mi-Kyeong Choi

Affiliations

  1. Department of Food Science and Nutrition, Kyungpook National University, Daegu 41566, Korea.
  2. Department of Food Science and Nutrition, Pukyong National University, Busan 48513, Korea.
  3. Department of Food and Nutrition, Kyung Hee University, Seoul 02447, Korea.
  4. Department of Food and Nutrition, Myongji University, Yongin 17058, Korea.
  5. Department of Food and Nutrition, Dongshin University, Naju 58245, Korea.
  6. Department of Food and Nutrition, Chonnam National University, Gwangju 61186, Korea.
  7. Department of Food and Nutrition, Chungbuk National University, Cheongju 28644, Korea.
  8. Division of Food Science, Kongju National University, Yesan 32439, Korea.

PMID: 26566521 PMCID: PMC4641988 DOI: 10.7762/cnr.2015.4.4.259

Abstract

Although it has been proposed that trace minerals have anti-oxidative functions and are related to the control of blood pressure, only a limited number of studies directly address the issue. Thus, the purpose of our study was to assess the intake of copper and manganese, which are trace minerals, and to clarify their relation to blood pressure. In a cross-sectional study, the blood pressure of 640 normotensive adults, from 19 to 69 year-old (320 males and 320 females), was measured, and its correlation with the intake of copper and manganese was assessed using a 24-hour dietary recall method. The average value of the blood pressure was 126.4/80.2 mmHg for the males and 117.8/75.8 mmHg for the females. The daily copper intake was 1.3 mg/day for the males and 1.2 mg/day for the females. For manganese, the daily intake was 4.2 mg/day for the males and 4.1 mg/day for the females. Although the copper intake of all subjects showed a positive correlation with the systolic and diastolic blood pressures, there was no significant correlation when the potential confounding factors were adjusted. The manganese intake of the male subjects had a significantly negative correlation with the systolic blood pressure after adjusting for gender, age, body mass index, and energy intake. In conclusion, the daily manganese intake of the normotensitve adults showed a significantly negative correlation with the systolic blood pressure indicating a possibility of a positive effect of manganese on blood pressure.

Keywords: Adult; Blood pressure; Copper; Dietary intake; Manganese

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