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Sanders E, Hill CM, Evans HJ, et al. The Development of a Screening Questionnaire for Obstructive Sleep Apnea in Children with Down Syndrome. Front Psychiatry. 2015;6:147doi: 10.3389/fpsyt.2015.00147.
Sanders, E., Hill, C. M., Evans, H. J., & Tuffrey, C. (2015). The Development of a Screening Questionnaire for Obstructive Sleep Apnea in Children with Down Syndrome. Frontiers in psychiatry, 6147. https://doi.org/10.3389/fpsyt.2015.00147
Sanders, Emma, et al. "The Development of a Screening Questionnaire for Obstructive Sleep Apnea in Children with Down Syndrome." Frontiers in psychiatry vol. 6 (2015): 147. doi: https://doi.org/10.3389/fpsyt.2015.00147
Sanders E, Hill CM, Evans HJ, Tuffrey C. The Development of a Screening Questionnaire for Obstructive Sleep Apnea in Children with Down Syndrome. Front Psychiatry. 2015 Oct 20;6:147. doi: 10.3389/fpsyt.2015.00147. eCollection 2015. PMID: 26539127; PMCID: PMC4611960.
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Front Psychiatry. 2015 Oct 20;6:147. doi: 10.3389/fpsyt.2015.00147. eCollection 2015.

The Development of a Screening Questionnaire for Obstructive Sleep Apnea in Children with Down Syndrome.

Frontiers in psychiatry

Emma Sanders, Catherine Mary Hill, Hazel Jean Evans, Catherine Tuffrey

Affiliations

  1. Faculty of Medicine, University of Southampton , Southampton , UK.
  2. Faculty of Medicine, University of Southampton , Southampton , UK ; Southampton Children's Hospital , Southampton , UK.
  3. Faculty of Medicine, University of Southampton , Southampton , UK ; Department of Child Health, Solent NHS Trust , Southampton , UK.

PMID: 26539127 PMCID: PMC4611960 DOI: 10.3389/fpsyt.2015.00147

Abstract

Obstructive sleep apnea is a condition which affects an estimated 50% of children with Down syndrome, particularly in their early years. It can cause serious sequelae in affected children but may not be recognized by parents or health professionals. Routine screening has been recommended in some countries, but is not standard practice. There are no validated questionnaire-based tools available to screen this population of children for this particular sleep-related disorder. Using existing validated sleep questionnaire items, we have developed a questionnaire to screen children with Down syndrome up to 6 years of age for obstructive sleep apnea, which corresponds with the recommendations made in UK national guidelines. This paper describes these first steps in demonstrating content validity for a new questionnaire, which will be subject to further in-depth psychometric analysis. Relevance, clarity, and age appropriateness were rated for 33 items using a content review questionnaire by a group of 18 health professionals with expertise in respiratory pediatrics, neurodevelopmental pediatrics, and sleep physiology. The content validity index was calculated for individual items and contributed to decisions about item inclusion. Scale level content validity index for the modified questionnaire of 14 items was at an accepted level of 0.78. Two parents of children with Down syndrome took part in cognitive interviews after completing the modified questionnaire. We describe the development of this 14 item questionnaire to screen for OSA in children with DS from infancy to 6 years.

Keywords: Down syndrome; measurement; obstructive sleep apnea; pediatrics; screening; sleep disorders

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