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Moreno-Fuquen R, Castillo JC, Becerra D, et al. Crystal structure of 2-fluoro-N-(1,3-thia-zol-2-yl)benzamide. Acta Crystallogr E Crystallogr Commun. 2015;71:o882-3doi: 10.1107/S2056989015019192.
Moreno-Fuquen, R., Castillo, J. C., Becerra, D., Camargo, H., & Henao, J. A. (2015). Crystal structure of 2-fluoro-N-(1,3-thia-zol-2-yl)benzamide. Acta crystallographica. Section E, Crystallographic communications, 71o882-3. https://doi.org/10.1107/S2056989015019192
Moreno-Fuquen, Rodolfo, et al. "Crystal structure of 2-fluoro-N-(1,3-thia-zol-2-yl)benzamide." Acta crystallographica. Section E, Crystallographic communications vol. 71 (2015): o882-3. doi: https://doi.org/10.1107/S2056989015019192
Moreno-Fuquen R, Castillo JC, Becerra D, Camargo H, Henao JA. Crystal structure of 2-fluoro-N-(1,3-thia-zol-2-yl)benzamide. Acta Crystallogr E Crystallogr Commun. 2015 Oct 24;71:o882-3. doi: 10.1107/S2056989015019192. eCollection 2015 Nov 01. PMID: 26594578; PMCID: PMC4645012.
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Acta Crystallogr E Crystallogr Commun. 2015 Oct 24;71:o882-3. doi: 10.1107/S2056989015019192. eCollection 2015 Nov 01.

Crystal structure of 2-fluoro-N-(1,3-thia-zol-2-yl)benzamide.

Acta crystallographica. Section E, Crystallographic communications

Rodolfo Moreno-Fuquen, Juan C Castillo, Diana Becerra, Hernando Camargo, José A Henao

Affiliations

  1. Departamento de Química - Facultad de Ciencias Naturales y Exactas, Universidad del Valle, Apartado 25360, Santiago de Cali, Colombia.
  2. Departamento de Química, Universidad de los Andes, Carrera 1 No 18A12, Bogotá, Colombia.
  3. Facultad de Química Ambiental, Universidad Santo Tomás, Campus Universitario Floridablanca, Santander, Colombia.
  4. Escuela de Química, Facultad de Ciencias, Universidad Industrial de Santander, Apartado 678, Bucaramanga, Colombia.

PMID: 26594578 PMCID: PMC4645012 DOI: 10.1107/S2056989015019192

Abstract

In the title compound, C10H7FN2OS, the mean plane of the central amide fragment (r.m.s. deviation = 0.048 Å) makes dihedral angles of 35.28 (8) and 10.14 (12)° with those of the fluoro-benzene and thia-zole rings, respectively. The thia-zole S and amide O atoms lie to the same side of the mol-ecule. In the crystal, pairs of N-H⋯N hydrogen bonds connect the mol-ecules into inversion dimers with R 2 (2)(8) motifs, and weak C-H⋯O inter-actions connect the mol-ecules into C(6) [001] chains. Together, the N-H⋯N and C-H⋯O hydrogen bonds generate (100) sheets.

Keywords: 1,3-thia­zole; benzamide; cancer cell-growth inhibitors; carboxamides; crystal structure; hydrogen bonding; thia­zole derivatives

References

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