Display options
Cite
Casey DL, van de Rijn M, Riley G, et al. Extraskeletal osteosarcoma of the hand: the role of marginal excision and adjuvant radiation therapy. Hand (N Y). 2015;10(4):602-6doi: 10.1007/s11552-015-9760-0.
Casey, D. L., van de Rijn, M., Riley, G., Tung, K. W., Mohler, D. G., & Donaldson, S. S. (2015). Extraskeletal osteosarcoma of the hand: the role of marginal excision and adjuvant radiation therapy. Hand (New York, N.Y.), 10(4), 602-6. https://doi.org/10.1007/s11552-015-9760-0
Casey, Dana L, et al. "Extraskeletal osteosarcoma of the hand: the role of marginal excision and adjuvant radiation therapy." Hand (New York, N.Y.) vol. 10,4 (2015): 602-6. doi: https://doi.org/10.1007/s11552-015-9760-0
Casey DL, van de Rijn M, Riley G, Tung KW, Mohler DG, Donaldson SS. Extraskeletal osteosarcoma of the hand: the role of marginal excision and adjuvant radiation therapy. Hand (N Y). 2015 Dec;10(4):602-6. doi: 10.1007/s11552-015-9760-0. Epub 2015 Apr 17. PMID: 26568711; PMCID: PMC4641083.
Copy Download .nbib Format: NLM
Share it on

Hand (N Y). 2015 Dec;10(4):602-6. doi: 10.1007/s11552-015-9760-0. Epub 2015 Apr 17.

Extraskeletal osteosarcoma of the hand: the role of marginal excision and adjuvant radiation therapy.

Hand (New York, N.Y.)

Dana L Casey, Matt van de Rijn, Geoffrey Riley, Ka-Wah Tung, David G Mohler, Sarah S Donaldson

Affiliations

  1. Department of Radiation Oncology, Stanford University, Stanford, CA USA.
  2. Department of Pathology, Stanford University, Stanford, CA USA.
  3. Department of Radiology, Stanford University, Stanford, CA USA.
  4. Department of Surgery, Stanford University, Stanford, CA USA.
  5. Department of Radiation Oncology, Stanford University, Stanford, CA USA ; Department of Radiation Oncology, Stanford University Cancer Center, 875 Blake Wilbur Drive, Stanford, CA 94305 USA.

PMID: 26568711 PMCID: PMC4641083 DOI: 10.1007/s11552-015-9760-0

Abstract

BACKGROUND: Extraskeletal osteosarcoma of the hand is rare, and its optimal modality of local control is not currently known.

METHODS: A literature search was performed to identify studies that describe the treatment and outcomes of extraskeletal osteosarcoma. A second literature search was performed to identify studies that describe the treatment and outcomes of extraskeletal osteosarcoma of the hand specifically.

RESULTS: The role of adjuvant radiation for extraskeletal osteosarcoma is not well defined. All cases in the literature describing treatment of extraskeletal osteosarcoma of the hand utilized amputation, and none of the patients described received radiation therapy. However, there are multiple reports showing excellent local control, minimal toxicity, and superior functional outcome with limb conservation and radiation rather than amputation of the hand in pediatric and adult soft tissue sarcoma.

CONCLUSION: For extraskeletal osteosarcoma of the hand, we recommend a treatment approach with the goal of preservation of form and function using limb-sparing surgery and planned postoperative radiation.

Keywords: Hand; Limb salvage; Osteosarcoma; Radiation therapy; Soft tissue sarcoma

References

  1. J Clin Oncol. 2002 Jan 15;20(2):521-7 - PubMed
  2. Cancer. 2002 Aug 15;95(4):852-61 - PubMed
  3. Ann Surg Oncol. 2005 Apr;12(4):322-31 - PubMed
  4. J Cancer Res Clin Oncol. 2005 Aug;131(8):520-6 - PubMed
  5. Am J Clin Oncol. 2006 Feb;29(1):62-5 - PubMed
  6. J Orthop Sci. 2007 Sep;12(5):424-9 - PubMed
  7. Sarcoma. 2000;4(3):119-23 - PubMed
  8. Int J Radiat Oncol Biol Phys. 2011 May 1;80(1):206-12 - PubMed
  9. Cancer. 1990 Dec 15;66(12):2482-91 - PubMed
  10. Hand (N Y). 2012 Mar;7(1):124-6 - PubMed
  11. J Bone Joint Surg Am. 2014 Jan 1;96(1):e2 - PubMed
  12. Am J Clin Oncol. 2016 Feb;39(1):32-6 - PubMed
  13. JBJS Case Connect. 2013 Jan-Mar;3(1):e6 - PubMed
  14. Cancer. 1987 Sep 1;60(5):1132-42 - PubMed
  15. Cancer. 1983 Feb 15;51(4):727-34 - PubMed
  16. Ann Surg. 1982 Sep;196(3):305-15 - PubMed
  17. J Natl Cancer Inst. 1995 Sep 6;87(17):1331-3 - PubMed
  18. Cancer. 1993 Aug 1;72(3):719-25 - PubMed
  19. Cancer. 1995 Dec 1;76(11):2253-9 - PubMed
  20. J Clin Oncol. 1998 Jan;16(1):197-203 - PubMed
  21. Am J Surg Pathol. 1998 May;22(5):588-94 - PubMed
  22. J Bone Joint Surg Am. 1998 May;80(5):725-9 - PubMed

Publication Types