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Lee SG, Shin IY, Hwang HS, et al. Multimodal Treatment of Skull Base Inflammatory Pseudotumor: Case Report. Brain Tumor Res Treat. 2015;3(2):122-6doi: 10.14791/btrt.2015.3.2.122.
Lee, S. G., Shin, I. Y., Hwang, H. S., & Choi, I. (2015). Multimodal Treatment of Skull Base Inflammatory Pseudotumor: Case Report. Brain tumor research and treatment, 3(2), 122-6. https://doi.org/10.14791/btrt.2015.3.2.122
Lee, Sang Gun, et al. "Multimodal Treatment of Skull Base Inflammatory Pseudotumor: Case Report." Brain tumor research and treatment vol. 3,2 (2015): 122-6. doi: https://doi.org/10.14791/btrt.2015.3.2.122
Lee SG, Shin IY, Hwang HS, Choi I. Multimodal Treatment of Skull Base Inflammatory Pseudotumor: Case Report. Brain Tumor Res Treat. 2015 Oct;3(2):122-6. doi: 10.14791/btrt.2015.3.2.122. Epub 2015 Oct 30. PMID: 26605269; PMCID: PMC4656889.
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Brain Tumor Res Treat. 2015 Oct;3(2):122-6. doi: 10.14791/btrt.2015.3.2.122. Epub 2015 Oct 30.

Multimodal Treatment of Skull Base Inflammatory Pseudotumor: Case Report.

Brain tumor research and treatment

Sang Gun Lee, Il Young Shin, Hyung Sik Hwang, Il Choi

Affiliations

  1. Department of Neurosurgery, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong, Korea.

PMID: 26605269 PMCID: PMC4656889 DOI: 10.14791/btrt.2015.3.2.122

Abstract

lnflammatory pseudotumor (IPT) is a rare, non-neoplastic inflammatory process. It is most commonly occurs in the orbit, but extension into brain parenchyma is uncommon. In a confirmed case of IPT, most cases show good improvement with steroid theraphy. A 50-year-old man with progressive left-eye visual disturbance and mass lesion was admitted in a hospital. A left orbital mass biopsy revealed what was highly suspected as an inflammatory pseudotumor. Steroid pulse therapy with dexamethasone, radiation therapy, and chemotherapy with amphotericin B were performed, but they were not effective in improving the condition of the patient. Revision open surgery was then performed. A follow-up brain enhancement computerized tomography showed an enlarged mass volume and hydrocephalus with periventricular enhancement. As an additional procedure, ventriculoperitoneal shunt and tuberculosis medication were administered. About 2 weeks later, clinical symptoms and radiologic findings improved. We present a case of intra-cranial IPT and discuss further treatment methods.

Keywords: Cavernous sinus; Central nervous system; Granuloma; Sphenoid sinus

Conflict of interest statement

The authors have no financial conflicts of interest.

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