Display options
Share it on

Biomed Opt Express. 2015 Oct 05;6(11):4255-72. doi: 10.1364/BOE.6.004255. eCollection 2015 Nov 01.

Analytical reconstructions of intensity modulated x-ray phase-contrast imaging of human scale phantoms.

Biomedical optics express

Bartłomiej Włodarczyk, Jakub Pietrzak

Affiliations

  1. Biomedical Physics Department, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warsaw, Poland.

PMID: 26600991 PMCID: PMC4646535 DOI: 10.1364/BOE.6.004255

Abstract

This paper presents analytical approach to modeling of a full planar and volumetric acquisition system with image reconstructions originated from partial illumination x-ray phase-contrast imaging at a human scale using graphics processor units. The model is based on x-ray tracing and wave optics methods to develop a numerical framework for predicting the performance of a preclinical phase-contrast imaging system of a human-scaled phantom. In this study, experimental images of simple numerical phantoms and high resolution anthropomorphic phantoms of head and thorax based on non-uniform rational b-spline shapes (NURBS) prove the correctness of the model. Presented results can be used to simulate the performance of partial illumination x-ray phase-contrast imaging system on various preclinical applications.

Keywords: (170.3880) Medical and biological imaging; (340.7440) X-ray imaging

References

  1. Phys Med Biol. 2007 Nov 21;52(22):6555-73 - PubMed
  2. Med Phys. 1998 Jan;25(1):114-20 - PubMed
  3. Opt Express. 2008 Mar 3;16(5):3223-41 - PubMed
  4. Eur J Radiol. 2008 Dec;68(3 Suppl):S13-7 - PubMed
  5. Med Phys. 2010 Jun;37(6):2473-9 - PubMed
  6. Nat Med. 1996 Apr;2(4):473-5 - PubMed
  7. Opt Lett. 1997 Jul 15;22(14):1059-61 - PubMed
  8. Med Phys. 1975 Nov-Dec;2(6):307-20 - PubMed
  9. Phys Med Biol. 2004 Aug 21;49(16):3573-83 - PubMed
  10. Med Phys. 2010 Sep;37(9):4902-15 - PubMed
  11. Med Phys. 2007 Feb;34(2):737-43 - PubMed
  12. Med Phys. 2005 Dec;32(12):3617-27 - PubMed
  13. Opt Express. 2010 Sep 13;18(19):19681-92 - PubMed
  14. Eur J Radiol. 2008 Dec;68(3 Suppl):S73-7 - PubMed
  15. Appl Opt. 2011 Apr 20;50(12):1765-9 - PubMed
  16. Phys Med Biol. 2013 Jan 7;58(1):R1-35 - PubMed
  17. Opt Express. 2010 Mar 1;18(5):4103-17 - PubMed
  18. Appl Opt. 1978 Dec 15;17(24):3990-8 - PubMed
  19. Phys Med Biol. 1997 Nov;42(11):2015-25 - PubMed
  20. Phys Med Biol. 1998 Oct;43(10):2845-52 - PubMed
  21. Med Phys. 2013 Feb;40(2):021909 - PubMed
  22. Phys Med. 2008 Sep;24(3):129-48 - PubMed

Publication Types