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J Ultrason. 2012 Sep;12(50):319-28. doi: 10.15557/JoU.2012.0017. Epub 2012 Sep 30.

The pathogenesis of rheumatoid arthritis in radiological studies. Part II: Imaging studies in rheumatoid arthritis.

Journal of ultrasonography

Iwona Sudoł-Szopińska, Katarzyna Zaniewicz-Kaniewska, Agnieszka Warczyńska, Genowefa Matuszewska, Fadhil Saied, Wojciech Kunisz

Affiliations

  1. Zak?ad Radiologii, Instytut Reumatologii, Warszawa, Polska.

PMID: 26673409 PMCID: PMC4582518 DOI: 10.15557/JoU.2012.0017

Abstract

Early diagnosis of rheumatoid arthritis followed by early initiation of treatment, prevent the destruction of joints and progression to disability in the majority of patients. A traditional X-ray fails to capture early inflammatory changes, while late changes (e.g. erosions) appear after a significant delay, once 20-30% of bone mass has been lost. Sonography and magnetic resonance imaging studies have shown that erosions are seen in the first 3 months from the appearance of symptoms in 10-26% of patients, while in 75% they are seen in the first 2 years of the disease. Power Doppler ultrasound and dynamic magnetic resonance studies allow for qualitative, semiquantitative and quantitative monitoring of the vascularization of the synovium. In addition, magnetic resonance enables assessment of the bone marrow. The ultrasonographic examination using a state-of-the-art apparatus with a high-frequency probe allows for images with great spatial resolution and for the visualization of soft tissues and bone surfaces. However, the changes seen in ultrasonography (synovial pathologies, the presence of exudate, tendons changes, cartilage and bone lesions, pathologies of tendon attachments and ligaments - enthesopathies) are not only specific for rheumatoid arthritis and occur in other rheumatic diseases. Qualitative methods are sufficient for diagnosing the disease through ultrasound or magnetic resonance imaging. Whereas semiquantitative and quantitative scales serve to monitor the disease course - efficacy of conservative treatment and qualification for radioisotope synovectomy or surgical synovectomy - and to assess treatment efficacy.

Keywords: bone marrow edema; magnetic resonance imaging; pathogenesis; radiographs; rheumatoid arthritis; ultrasound

References

  1. Arthritis Rheum. 2003 Jan;48(1):64-71 - PubMed
  2. Eur J Radiol. 2009 Aug;71(2):189-96 - PubMed
  3. J Rheumatol. 2003 Jun;30(6):1366-75 - PubMed
  4. J Rheumatol. 2003 Jun;30(6):1376-9 - PubMed
  5. Ann Rheum Dis. 2009 May;68(5):751-6 - PubMed
  6. Arthritis Rheum. 2008 Oct;58(10):2958-67 - PubMed
  7. Best Pract Res Clin Rheumatol. 2008 Dec;22(6):1109-26 - PubMed
  8. Rheumatology (Oxford). 2008 Jan;47(1):13-21 - PubMed
  9. J Rheumatol. 2003 Jun;30(6):1385-6 - PubMed
  10. Rheumatology (Oxford). 2009 Mar;48(3):254-7 - PubMed
  11. Arthritis Rheum. 1988 Mar;31(3):315-24 - PubMed
  12. Rheumatology (Oxford). 2000 Apr;39(4):407-16 - PubMed
  13. Best Pract Res Clin Rheumatol. 2004 Dec;18(6):861-79 - PubMed
  14. Rheumatology (Oxford). 2009 Apr;48(4):378-82 - PubMed
  15. Arthritis Res Ther. 2008;10 (5):222 - PubMed
  16. Radiology. 2009 Oct;253(1):234-40 - PubMed
  17. Skeletal Radiol. 2008 Mar;37(3):201-7 - PubMed
  18. Arthritis Rheum. 1999 May;42(5):918-29 - PubMed
  19. Radiology. 1990 Aug;176(2):473-7 - PubMed
  20. Magn Reson Imaging. 1998 Sep;16(7):743-54 - PubMed
  21. Radiology. 2010 Sep;256(3):863-9 - PubMed
  22. Arthritis Rheum. 2004 Feb;50(2):674-5; author reply 675-6 - PubMed

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