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Leguia M, Loyola S, Rios J, et al. Full Genomic Characterization of a Saffold Virus Isolated in Peru. Pathogens. 2015;4(4):816-25doi: 10.3390/pathogens4040816.
Leguia, M., Loyola, S., Rios, J., Juarez, D., Guevara, C., Silva, M., Prieto, K., Wiley, M., Kasper, M. R., Palacios, G., & Bausch, D. G. (2015). Full Genomic Characterization of a Saffold Virus Isolated in Peru. Pathogens (Basel, Switzerland), 4(4), 816-25. https://doi.org/10.3390/pathogens4040816
Leguia, Mariana, et al. "Full Genomic Characterization of a Saffold Virus Isolated in Peru." Pathogens (Basel, Switzerland) vol. 4,4 (2015): 816-25. doi: https://doi.org/10.3390/pathogens4040816
Leguia M, Loyola S, Rios J, Juarez D, Guevara C, Silva M, Prieto K, Wiley M, Kasper MR, Palacios G, Bausch DG. Full Genomic Characterization of a Saffold Virus Isolated in Peru. Pathogens. 2015 Nov 20;4(4):816-25. doi: 10.3390/pathogens4040816. PMID: 26610576; PMCID: PMC4693166.
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Pathogens. 2015 Nov 20;4(4):816-25. doi: 10.3390/pathogens4040816.

Full Genomic Characterization of a Saffold Virus Isolated in Peru.

Pathogens (Basel, Switzerland)

Mariana Leguia, Steev Loyola, Jane Rios, Diana Juarez, Carolina Guevara, Maria Silva, Karla Prieto, Michael Wiley, Matthew R Kasper, Gustavo Palacios, Daniel G Bausch

Affiliations

  1. Naval Medical Research Unit No. 6 (NAMRU-6), Callao 2, Peru. [email protected].
  2. Naval Medical Research Unit No. 6 (NAMRU-6), Callao 2, Peru. [email protected].
  3. Naval Medical Research Unit No. 6 (NAMRU-6), Callao 2, Peru. [email protected].
  4. Naval Medical Research Unit No. 6 (NAMRU-6), Callao 2, Peru. [email protected].
  5. Naval Medical Research Unit No. 6 (NAMRU-6), Callao 2, Peru. [email protected].
  6. Naval Medical Research Unit No. 6 (NAMRU-6), Callao 2, Peru. [email protected].
  7. Center for Genome Sciences, United States Army Medical Research Institute for Infectious Diseases (USAMRIID), Frederick, MD 21702, USA. [email protected].
  8. Center for Genome Sciences, United States Army Medical Research Institute for Infectious Diseases (USAMRIID), Frederick, MD 21702, USA. [email protected].
  9. Naval Medical Research Unit No. 6 (NAMRU-6), Callao 2, Peru. [email protected].
  10. Center for Genome Sciences, United States Army Medical Research Institute for Infectious Diseases (USAMRIID), Frederick, MD 21702, USA. [email protected].
  11. Naval Medical Research Unit No. 6 (NAMRU-6), Callao 2, Peru. [email protected].

PMID: 26610576 PMCID: PMC4693166 DOI: 10.3390/pathogens4040816

Abstract

While studying respiratory infections of unknown etiology we detected Saffold virus in an oropharyngeal swab collected from a two-year-old female suffering from diarrhea and respiratory illness. The full viral genome recovered by deep sequencing showed 98% identity to a previously described Saffold strain isolated in Japan. Phylogenetic analysis confirmed the Peruvian Saffold strain belongs to genotype 3 and is most closely related to strains that have circulated in Asia. This is the first documented case report of Saffold virus in Peru and the only complete genomic characterization of a Saffold-3 isolate from the Americas.

Keywords: Cardiovirus; Peru; Saffold virus; full genome

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