Display options
Cite
Ren H, Wang W, Feng Q, et al. A Novel Intelligent Vascular Stent: Preparation and Characterization of Hydrophobic Steel Mesh Stent with Liquid Surface Tension Response. J Nanosci Nanotechnol. 2015;15(12):9643-9doi: 10.1166/jnn.2015.11647.
Ren, H., Wang, W., Feng, Q., Mao, J., Wang, M., Cheng, H., Zhou, Y., & Jiang, Z. (2015). A Novel Intelligent Vascular Stent: Preparation and Characterization of Hydrophobic Steel Mesh Stent with Liquid Surface Tension Response. Journal of nanoscience and nanotechnology, 15(12), 9643-9. https://doi.org/10.1166/jnn.2015.11647
Ren, Hui, et al. "A Novel Intelligent Vascular Stent: Preparation and Characterization of Hydrophobic Steel Mesh Stent with Liquid Surface Tension Response." Journal of nanoscience and nanotechnology vol. 15,12 (2015): 9643-9. doi: https://doi.org/10.1166/jnn.2015.11647
Ren H, Wang W, Feng Q, Mao J, Wang M, Cheng H, Zhou Y, Jiang Z. A Novel Intelligent Vascular Stent: Preparation and Characterization of Hydrophobic Steel Mesh Stent with Liquid Surface Tension Response. J Nanosci Nanotechnol. 2015 Dec;15(12):9643-9. doi: 10.1166/jnn.2015.11647. PMID: 26682391.
Copy Download .nbib Format: NLM
Share it on

J Nanosci Nanotechnol. 2015 Dec;15(12):9643-9. doi: 10.1166/jnn.2015.11647.

A Novel Intelligent Vascular Stent: Preparation and Characterization of Hydrophobic Steel Mesh Stent with Liquid Surface Tension Response.

Journal of nanoscience and nanotechnology

Hui Ren, Wenjuan Wang, Qiang Feng, Jiao Mao, Mingqiang Wang, Hao Cheng, Yi Zhou, ZaiXing Jiang

PMID: 26682391 DOI: 10.1166/jnn.2015.11647

Abstract

An intelligent vascular stent was fabricated from a hydrophobic mesh tube, which cans in-situ release thrombolytic drugs only by an injection of nitroglycerin solution. The mesh with 80# pore size has the highest hydrophobic property and the most sensitive response performance after 3.00 wt% (Heptadecafluoro-1,1,2,2,-tetradecyl)trimethoxysilane (HFTES) treatment. This may be due to the larger hydrophobic effective area and more active fluorine groups of 80# mesh surface treated by 3.00 wt% HFTES. It was proved that the "thrombolytic medicine" could be easily and efficiently into the interior of the stent after triggered only by an injection of nitroglycerin liquid. The in-situ thrombolytic effect and the spent time were satisfactory. The thrombosis had been completely dissolved. This technology provides a potential therapy for vascular restenosis and has great potential applications in the therapy for in-stent restenosis.

Publication Types