Display options
Cite
De Clercq E. An Odyssey in antiviral drug development-50 years at the Rega Institute: 1964-2014. Acta Pharm Sin B. 2015;5(6):520-43doi: 10.1016/j.apsb.2015.09.001.
De Clercq, E. (2015). An Odyssey in antiviral drug development-50 years at the Rega Institute: 1964-2014. Acta pharmaceutica Sinica. B, 5(6), 520-43. https://doi.org/10.1016/j.apsb.2015.09.001
De Clercq, Erik. "An Odyssey in antiviral drug development-50 years at the Rega Institute: 1964-2014." Acta pharmaceutica Sinica. B vol. 5,6 (2015): 520-43. doi: https://doi.org/10.1016/j.apsb.2015.09.001
De Clercq E. An Odyssey in antiviral drug development-50 years at the Rega Institute: 1964-2014. Acta Pharm Sin B. 2015 Nov;5(6):520-43. doi: 10.1016/j.apsb.2015.09.001. Epub 2015 Nov 02. PMID: 26713268; PMCID: PMC4675811.
Copy Download .nbib Format: NLM
Share it on

Acta Pharm Sin B. 2015 Nov;5(6):520-43. doi: 10.1016/j.apsb.2015.09.001. Epub 2015 Nov 02.

An Odyssey in antiviral drug development-50 years at the Rega Institute: 1964-2014.

Acta pharmaceutica Sinica. B

Erik De Clercq

Affiliations

  1. Rega Institute for Medical Research, KU Leuven, Leuven B-3000, Belgium.

PMID: 26713268 PMCID: PMC4675811 DOI: 10.1016/j.apsb.2015.09.001

[No abstract available.]

Keywords: Antiviral drug; Atripla®; Brivudin; Complera®/Eviplera®; Erik De Clercq; FV-100; Holý's legacy; Interferon; Mozobil®; Poly(I)·poly(C); Polyacrylic acid; Reverse transcriptase; Sofosbuvir; Stavudine; Stribild®; Suramin; Tenofovir alafenamide (TAF); Tenofovir disoproxil fumarate (TDF); Truvada®; Valaciclovir

References

  1. Proc Natl Acad Sci U S A. 1979 Jun;76(6):2947-51 - PubMed
  2. Nature. 1970 Jun 27;226(5252):1211-3 - PubMed
  3. J Virol. 1968 Sep;2(9):886-93 - PubMed
  4. Proc Natl Acad Sci U S A. 1967 Sep;58(3):1004-10 - PubMed
  5. J Med Chem. 2005 Mar 24;48(6):1901-9 - PubMed
  6. Antiviral Res. 1987 Dec;8(5-6):261-72 - PubMed
  7. Nature. 1970 Jun 27;226(5252):1209-11 - PubMed
  8. Science. 1971 Jul 16;173(3993):260-2 - PubMed
  9. Cancer Lett. 1979 Nov;8(1):9-22 - PubMed
  10. J Antimicrob Chemother. 2007 Dec;60(6):1316-30 - PubMed
  11. Antiviral Res. 1997 Aug;35(3):147-56 - PubMed
  12. J Clin Invest. 1970 Aug;49(8):1565-77 - PubMed
  13. J Biol Chem. 1975 Apr 10;250(7):2521-31 - PubMed
  14. Nat Rev Drug Discov. 2006 Dec;5(12):1015-25 - PubMed
  15. Nature. 1970 Apr 25;226(5243):364-6 - PubMed
  16. Biochem Pharmacol. 2015 Jan 1;93(1):1-10 - PubMed
  17. Br Med J. 1980 Nov 1;281(6249):1178 - PubMed
  18. Nat Rev Microbiol. 2004 Sep;2(9):704-20 - PubMed
  19. Nature. 1969 Jun 21;222(5199):1148-52 - PubMed
  20. Antimicrob Agents Chemother. 1998 Mar;42(3):612-7 - PubMed
  21. Arch Ophthalmol. 1985 Sep;103(9):1393-7 - PubMed
  22. Nat Rev Drug Discov. 2007 Dec;6(12):1001-18 - PubMed
  23. Science. 1974 Dec 27;186(4170):1172-8 - PubMed
  24. Mol Pharm. 2013 Feb 4;10(2):459-66 - PubMed
  25. Arch Ophthalmol. 1982 Aug;100(8):1337-40 - PubMed
  26. Biochem Pharmacol. 2012 Aug 1;84(3):241-8 - PubMed
  27. J Exp Med. 1997 Oct 20;186(8):1383-8 - PubMed
  28. Proc Natl Acad Sci U S A. 1974 Jan;71(1):182-6 - PubMed
  29. Nature. 1986 Oct 2-8;323(6087):464-7 - PubMed
  30. Antimicrob Agents Chemother. 2005 May;49(5):1898-906 - PubMed
  31. Proc Natl Acad Sci U S A. 1992 Jun 15;89(12):5286-90 - PubMed
  32. J Mol Biol. 1971 Feb 28;56(1):83-100 - PubMed
  33. Proc Natl Acad Sci U S A. 1986 Mar;83(6):1911-5 - PubMed
  34. Biochem Pharmacol. 2013 Mar 15;85(6):727-44 - PubMed
  35. Antimicrob Agents Chemother. 2011 Jun;55(6):2847-54 - PubMed
  36. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1091-8 - PubMed
  37. J Med Chem. 2007 Nov 15;50(23):5765-72 - PubMed
  38. Science. 1978 May 5;200(4341):563-5 - PubMed
  39. Nat Rev Drug Discov. 2005 Nov;4(11):928-40 - PubMed
  40. Biochem Pharmacol. 2009 Jun 1;77(11):1655-64 - PubMed
  41. Antivir Chem Chemother. 2010 Jan 05;20(3):107-15 - PubMed
  42. Proc Natl Acad Sci U S A. 1967 Oct;58(4):1719-22 - PubMed
  43. Antimicrob Agents Chemother. 1987 Jun;31(6):907-10 - PubMed
  44. Proc Natl Acad Sci U S A. 1967 Nov;58(5):2102-8 - PubMed
  45. Nat Rev Drug Discov. 2003 Jul;2(7):581-7 - PubMed
  46. J Med Chem. 1989 Dec;32(12):2507-9 - PubMed
  47. J Pharmacol Exp Ther. 2001 Apr;297(1):1-10 - PubMed
  48. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1085-90 - PubMed
  49. J Med Chem. 1983 Apr;26(4):602-4 - PubMed
  50. J Med Chem. 2002 Apr 25;45(9):1918-29 - PubMed
  51. Biochem Biophys Res Commun. 1989 Dec 29;165(3):1375-81 - PubMed
  52. Antimicrob Agents Chemother. 1993 Feb;37(2):332-8 - PubMed
  53. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5716-20 - PubMed
  54. Antiviral Res. 1987 Jan;7(1):1-10 - PubMed
  55. Science. 1969 Sep 12;165(3898):1137-9 - PubMed
  56. Biochem Pharmacol. 2013 Sep 15;86(6):711-25 - PubMed
  57. Arch Ophthalmol. 1982 Apr;100(4):653-6 - PubMed
  58. Pharmacol Ther. 2010 Dec;128(3):509-18 - PubMed
  59. Antimicrob Agents Chemother. 1980 Jan;17(1):8-12 - PubMed
  60. Arch Ophthalmol. 1984 Jan;102(1):140-2 - PubMed
  61. J Med Chem. 2007 Mar 8;50(5):1069-77 - PubMed
  62. Antimicrob Agents Chemother. 1987 Dec;31(12):1879-81 - PubMed
  63. Biochem Pharmacol. 2014 Jun 15;89(4):441-52 - PubMed
  64. J Immunol. 1969 Nov;103(5):899-906 - PubMed
  65. Biochem Biophys Res Commun. 1987 Jan 15;142(1):128-34 - PubMed
  66. Antimicrob Agents Chemother. 1998 Jul;42(7):1568-73 - PubMed
  67. Nature. 1978 Apr 13;272(5654):583-5 - PubMed
  68. J Med Chem. 1999 Nov 4;42(22):4479-84 - PubMed
  69. J Virol. 1968 Sep;2(9):878-85 - PubMed
  70. Med Res Rev. 2013 Nov;33(6):1278-303 - PubMed
  71. Nat Rev Drug Discov. 2002 Jan;1(1):13-25 - PubMed
  72. J Med Chem. 2000 Dec 28;43(26):4993-7 - PubMed
  73. Antimicrob Agents Chemother. 2000 Jun;44(6):1667-73 - PubMed
  74. Science. 1995 Nov 17;270(5239):1197-9 - PubMed
  75. Biochem Pharmacol. 2013 Nov 15;86(10):1397-410 - PubMed
  76. Med Res Rev. 2008 Jan;28(1):1-38 - PubMed
  77. Proc Natl Acad Sci U S A. 1967 Aug;58(2):782-9 - PubMed
  78. Proc Natl Acad Sci U S A. 1985 Oct;82(20):7096-100 - PubMed
  79. Biochem Pharmacol. 2011 Jul 15;82(2):99-109 - PubMed
  80. Science. 1984 Oct 12;226(4671):172-4 - PubMed
  81. N Engl J Med. 1984 Mar 8;310(10):609-13 - PubMed
  82. Antimicrob Agents Chemother. 1994 Apr;38(4):668-74 - PubMed
  83. Antimicrob Agents Chemother. 2005 Mar;49(3):1081-6 - PubMed

Publication Types