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Solarino G, Vicenti G, Spinarelli A, et al. ASSESSING BONE MINERAL DENSITY IN ITALIAN ADULT CYSTIC FIBROSIS PATIENTS: A CROSS SECTIONAL STUDY. J Biol Regul Homeost Agents. 2015;29(4):79-85
Solarino, G., Vicenti, G., Spinarelli, A., Abate, A., Carrozzo, M., Cagnetta, V., & Moretti, B. (2015). ASSESSING BONE MINERAL DENSITY IN ITALIAN ADULT CYSTIC FIBROSIS PATIENTS: A CROSS SECTIONAL STUDY. Journal of biological regulators and homeostatic agents, 29(4), 79-85.
Solarino, G, et al. "ASSESSING BONE MINERAL DENSITY IN ITALIAN ADULT CYSTIC FIBROSIS PATIENTS: A CROSS SECTIONAL STUDY." Journal of biological regulators and homeostatic agents vol. 29,4 (2015): 79-85.
Solarino G, Vicenti G, Spinarelli A, Abate A, Carrozzo M, Cagnetta V, Moretti B. ASSESSING BONE MINERAL DENSITY IN ITALIAN ADULT CYSTIC FIBROSIS PATIENTS: A CROSS SECTIONAL STUDY. J Biol Regul Homeost Agents. 2015 Oct-Dec;29(4):79-85. PMID: 26652493.
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J Biol Regul Homeost Agents. 2015 Oct-Dec;29(4):79-85.

ASSESSING BONE MINERAL DENSITY IN ITALIAN ADULT CYSTIC FIBROSIS PATIENTS: A CROSS SECTIONAL STUDY.

Journal of biological regulators and homeostatic agents

G Solarino, G Vicenti, A Spinarelli, A Abate, M Carrozzo, V Cagnetta, B Moretti

Affiliations

  1. Department of Neuroscience and Organs of Sense, Orthopedics Section, Faculty of Medicine and Surgery, University of Bari, Bari, Italy.
  2. Department of Orthopedics and Traumatology, Monsignor Raffaele Dimiccoli Hospital, Barletta, Italy.
  3. Department of Neurology, Neurorehabilitation and Spinal Unit, IRCCS Maugeri Foundation, Cassano Murge, Italy.

PMID: 26652493

Abstract

The purpose of this study was to assess bone mineral density in a cystic fibrosis (CF) outpatient clinic population and to investigate the relationship between BMD and forced expiratory volume in one second (FEV1), DEXA T-scores and 25-hidroxivitamin D (25-OHD) serum levels. We examined a consecutive series of 44 CF patients. Bone mass density was measured by dual-photon X-ray absorptiometry of lumbar spine and femur (total and neck) and lung function was performed in all patients. Medication data were obtained from medical records. A correlation analysis was performed to determine the relationship between BMD and forced expiratory volume in one second (FEV1), DEXA T-scores and 25-hidroxivitamin D (25-OHD) serum levels. In the results, age showed a significant inverse correlation indicating that as the age increases, bone density decreases and we concluded that most CF patients have low BMD and that there is a positive correlation with lung function and an inverse correlation with age.

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