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J Biol Regul Homeost Agents. 2015 Oct-Dec;29(4):121-9.

DOES TOTAL KNEE REPLACEMENT MODIFY FLEXION AXIS OF THE KNEE ON FRONTAL AND AXIAL PLANE REGARDLESS FROM LIMB ALIGNMENT?.

Journal of biological regulators and homeostatic agents

D Bruni, L Bragonzoni, M Bontempi, F Iacono, M P Neri, S Bignozzi, S Zaffagnini, M Marcacci

Affiliations

  1. 2nd Orthopaedics and Traumatologic Clinic, Rizzoli Orthopaedic Institute, Bologna, Italy.
  2. Biomedical and Neuromotor Sciences - DIBINEM - The Alma Mater Studiorum, University of Bologna, Italy.
  3. Biomechanics Laboratory, Codivilla-Putti Research Center, Bologna, Italy.
  4. Orthokey Italia Srl, Italy.
  5. 2nd Orthopaedics and Traumatologic Clinic, Rizzoli Orthopaedic Institute, Bologna, Italy; Biomechanics and Technologic Innovation Laboratory and Nanobiotechnology Laboratory, Codivilla-Putti Research Center, Bologna University, Italy.

PMID: 26652498

Abstract

The optimal reference for rotational positioning of femoral component in total knee replacement (TKR) is debated. Navigation has been suggested for intra-op acquisition of patient’s specific kinematics and functional flexion axis (FFA). The main purpose of the present study is to prospectively investigate whether pre-operative FFA in patients with osteoarthritis (OA) and varus alignment changes after TKR and whether a correlation exists between post-op FFA and pre-op alignment. A navigated TKR was performed in 108 patients using a specific software to acquire passive joint kinematics before and after TKR. The knee was cycled through three passive range of motions (PROM), from 0° to 120°. FFA was computed using the mean helical axis algorithm. The angle between FFA and surgical TEA was determined on frontal (αf) and axial (αa) plane. The pre- and post-op hip-knee-ankle angle (HKA) was determined. Post-op FFA was different from pre-op FFA only on frontal plane. No significant difference was found on axial plane. No correlation was found between HKA-pre and αA-pre. A significant correlation was found between HKA-pre and αF–pre. The study concluded that TKR modifies FFA only on frontal plane. No difference was found on axial plane. Pre-op FFA is in a more varus position respect to TEA. The position of FFA on frontal plane is dependent on limb alignment. The present study has demonstrated TKR modifies the position of FFA only on frontal plane. The position of FFA on axial plane is not dependent on the amount of varus deformity and is not influenced by TKR. Level of evidence, IV, case series.

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