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Alzahrani T, Kay D, Alqahtani SA, et al. Levetiracetam-induced pancytopenia. Epilepsy Behav Case Rep. 2015;4:45-7doi: 10.1016/j.ebcr.2015.06.001.
Alzahrani, T., Kay, D., Alqahtani, S. A., Makke, Y., Lesky, L., & Koubeissi, M. Z. (2015). Levetiracetam-induced pancytopenia. Epilepsy & behavior case reports, 445-7. https://doi.org/10.1016/j.ebcr.2015.06.001
Alzahrani, Talal, et al. "Levetiracetam-induced pancytopenia." Epilepsy & behavior case reports vol. 4 (2015): 45-7. doi: https://doi.org/10.1016/j.ebcr.2015.06.001
Alzahrani T, Kay D, Alqahtani SA, Makke Y, Lesky L, Koubeissi MZ. Levetiracetam-induced pancytopenia. Epilepsy Behav Case Rep. 2015 Jul 24;4:45-7. doi: 10.1016/j.ebcr.2015.06.001. eCollection 2015. PMID: 26744695; PMCID: PMC4681875.
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Epilepsy Behav Case Rep. 2015 Jul 24;4:45-7. doi: 10.1016/j.ebcr.2015.06.001. eCollection 2015.

Levetiracetam-induced pancytopenia.

Epilepsy & behavior case reports

Talal Alzahrani, Dana Kay, Saeed A Alqahtani, Yamane Makke, Linda Lesky, Mohamad Z Koubeissi

Affiliations

  1. Department of Internal Medicine, George Washington University, Washington DC, USA; Department of Internal Medicine, Taibah University, Medina, KSA.
  2. Department of Internal Medicine, George Washington University, Washington DC, USA.
  3. Department of Neurology, George Washington University, Washington DC, USA.

PMID: 26744695 PMCID: PMC4681875 DOI: 10.1016/j.ebcr.2015.06.001

Abstract

Pancytopenia is a rare side effect of levetiracetam (LEV) that is associated with severe morbidity that requires hospitalization. Here, we report a patient with a right temporoparietal tumor who underwent a temporal craniotomy with resection of the mass and was started on LEV for seizure prophylaxis per the neurosurgery local protocol. The patient developed LEV-induced pancytopenia, which was successfully managed by discontinuation of this medication. Our report aims to increase awareness of this rare cause of pancytopenia among clinicians.

Keywords: Adverse effects; Glioblastoma multiforme; Levetiracetam; Pancytopenia

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