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Zhang F, Ren T, Wu J. TGF-β1 induces apoptosis of bone marrow-derived mesenchymal stem cells via regulation of mitochondrial reactive oxygen species production. Exp Ther Med. 2015;10(3):1224-1228doi: 10.3892/etm.2015.2590.
Zhang, F., Ren, T., & Wu, J. (2015). TGF-β1 induces apoptosis of bone marrow-derived mesenchymal stem cells via regulation of mitochondrial reactive oxygen species production. Experimental and therapeutic medicine, 10(3), 1224-1228. https://doi.org/10.3892/etm.2015.2590
Zhang, Fenxi, et al. "TGF-β1 induces apoptosis of bone marrow-derived mesenchymal stem cells via regulation of mitochondrial reactive oxygen species production." Experimental and therapeutic medicine vol. 10,3 (2015): 1224-1228. doi: https://doi.org/10.3892/etm.2015.2590
Zhang F, Ren T, Wu J. TGF-β1 induces apoptosis of bone marrow-derived mesenchymal stem cells via regulation of mitochondrial reactive oxygen species production. Exp Ther Med. 2015 Sep;10(3):1224-1228. doi: 10.3892/etm.2015.2590. Epub 2015 Jun 23. PMID: 26622469; PMCID: PMC4533206.
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Exp Ther Med. 2015 Sep;10(3):1224-1228. doi: 10.3892/etm.2015.2590. Epub 2015 Jun 23.

TGF-β1 induces apoptosis of bone marrow-derived mesenchymal stem cells via regulation of mitochondrial reactive oxygen species production.

Experimental and therapeutic medicine

Fenxi Zhang, Tongming Ren, Junfang Wu

Affiliations

  1. Department of Anatomy, Sanquan College, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China ; Stem Cell Center, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.
  2. Department of Anatomy, Sanquan College, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.
  3. Morphology Laboratory, Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.

PMID: 26622469 PMCID: PMC4533206 DOI: 10.3892/etm.2015.2590

Abstract

Bone marrow-derived mesenchymal stem cells (BMSCs) are the most promising seed cells in regenerative medicine. Our previous study demonstrated that transforming growth factor (TGF)-β1 induced BMSC senescence

Keywords: apoptosis; bone marrow-derived mesenchymal stem cells; mitochondrial reactive oxygen species; transforming growth factor-β1

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