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Wang H, Deng Q, Zhou Z, et al. Ag2CO3/CA-AA-AmidPhos Multifunctional Catalysis in the Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides. Org Lett. 2016;18(3):404-7doi: 10.1021/acs.orglett.5b03430.
Wang, H., Deng, Q., Zhou, Z., Hu, S., Liu, Z., & Zhou, L. Y. (2016). Ag2CO3/CA-AA-AmidPhos Multifunctional Catalysis in the Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides. Organic letters, 18(3), 404-7. https://doi.org/10.1021/acs.orglett.5b03430
Wang, Haifei, et al. "Ag2CO3/CA-AA-AmidPhos Multifunctional Catalysis in the Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides." Organic letters vol. 18,3 (2016): 404-7. doi: https://doi.org/10.1021/acs.orglett.5b03430
Wang H, Deng Q, Zhou Z, Hu S, Liu Z, Zhou LY. Ag2CO3/CA-AA-AmidPhos Multifunctional Catalysis in the Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides. Org Lett. 2016 Feb 05;18(3):404-7. doi: 10.1021/acs.orglett.5b03430. Epub 2016 Jan 08. PMID: 26745747.
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Org Lett. 2016 Feb 05;18(3):404-7. doi: 10.1021/acs.orglett.5b03430. Epub 2016 Jan 08.

Ag2CO3/CA-AA-AmidPhos Multifunctional Catalysis in the Enantioselective 1,3-Dipolar Cycloaddition of Azomethine Ylides.

Organic letters

Haifei Wang, Qifu Deng, Zhipeng Zhou, Shunqin Hu, Zhiguo Liu, Li-Yi Zhou

Affiliations

  1. School of Packaging and Materials Engineering, Hunan University of Technology , Zhuzhou 412007, Hunan Province, P.R. China.

PMID: 26745747 DOI: 10.1021/acs.orglett.5b03430

Abstract

The new Ag2CO3/CA-AA-amidphos complexes have been demonstrated as highly efficient multifunctional catalysts in the asymmetric 1,3-dipolar cycloaddition of azomethine ylides. Under optimal conditions, highly functionalized endo-4 pyrrolidines were obtained with excellent yields (up to 99% yield) and enantioselectivities (up to 96% ee).

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