Display options
Cite
Mark J, Bush S, Glazer E, et al. Metastatic VIPoma presenting as an ovarian mass. Int J Surg Case Rep. 2015;17:167-9doi: 10.1016/j.ijscr.2015.11.006.
Mark, J., Bush, S., Glazer, E., Strosberg, J., Saglam, O., & Apte, S. M. (2015). Metastatic VIPoma presenting as an ovarian mass. International journal of surgery case reports, 17167-9. https://doi.org/10.1016/j.ijscr.2015.11.006
Mark, Jaron, et al. "Metastatic VIPoma presenting as an ovarian mass." International journal of surgery case reports vol. 17 (2015): 167-9. doi: https://doi.org/10.1016/j.ijscr.2015.11.006
Mark J, Bush S, Glazer E, Strosberg J, Saglam O, Apte SM. Metastatic VIPoma presenting as an ovarian mass. Int J Surg Case Rep. 2015;17:167-9. doi: 10.1016/j.ijscr.2015.11.006. Epub 2015 Nov 23. PMID: 26657531; PMCID: PMC4701860.
Copy Download .nbib Format: NLM
Share it on

Int J Surg Case Rep. 2015;17:167-9. doi: 10.1016/j.ijscr.2015.11.006. Epub 2015 Nov 23.

Metastatic VIPoma presenting as an ovarian mass.

International journal of surgery case reports

Jaron Mark, Stephen Bush, Evan Glazer, Jonathan Strosberg, Ozlen Saglam, Sachin M Apte

Affiliations

  1. University of South Florida, 12901 Bruce B. Downs Blvd, Tampa, FL, USA.
  2. H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA.
  3. H. Lee Moffitt Cancer Center, 12902 Magnolia Drive, Tampa, FL 33612, USA. Electronic address: [email protected].

PMID: 26657531 PMCID: PMC4701860 DOI: 10.1016/j.ijscr.2015.11.006

Abstract

INTRODUCTION: Pancreatic VIPomas are exceedingly rare, with an annual incidence of less than 1 per million. Most VIPomas are metastatic at diagnosis, with the liver being the most common site of spread.

PRESENTATION OF CASE: We describe a highly unusual case of a metastatic pancreatic VIPoma to an ovary in a 54 year-old patient. She was ten years out from her initial diagnosis when routine CT scan showed an enlarging left adnexal mass. After having both ovaries removed laparoscopically the final pathology was consistent with her pancreatic primary. To our knowledge, there has been only one other such case described in the literature.

DISCUSSION: In this case, pathology revealed metastatic neuroendocrine tumor involving both the left and right ovaries despite only the right ovary apparently enlarging. In our literature search, only two other cases of metastatic PNET to the ovaries have been reported. One case was a glucagonoma and the other a VIPoma. We recommend that clinicians consider referral of patients with metastatic NET and ovarian metastases to gynecologic surgery for consideration of surgical resection.

CONCLUSION: In conclusion, this case proves that although uncommon, PNET can show metastases in both ovaries even a decade after initial diagnosis.

Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

Keywords: Gynecologic neuroendocrine tumors; Neuroendocrine tumors; Ovarian cancer; PNET; Pancreatic cancer; VIPoma

References

  1. Gynecol Oncol. 2007 Jul;106(1):65-8 - PubMed
  2. Endocr Res. 2011;36(1):35-43 - PubMed
  3. JOP. 2013 Sep 10;14(5):510-4 - PubMed
  4. Dtsch Med Wochenschr. 1995 Oct 27;120(43):1463-7 - PubMed

Publication Types