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Tran J, Schwarzkopf R. Local infiltration anesthesia with steroids in total knee arthroplasty: A systematic review of randomized control trials. J Orthop. 2015;12:S44-50doi: 10.1016/j.jor.2015.01.017.
Tran, J., & Schwarzkopf, R. (2015). Local infiltration anesthesia with steroids in total knee arthroplasty: A systematic review of randomized control trials. Journal of orthopaedics, 12S44-50. https://doi.org/10.1016/j.jor.2015.01.017
Tran, Jonathan, and Schwarzkopf, Ran. "Local infiltration anesthesia with steroids in total knee arthroplasty: A systematic review of randomized control trials." Journal of orthopaedics vol. 12 (2015): S44-50. doi: https://doi.org/10.1016/j.jor.2015.01.017
Tran J, Schwarzkopf R. Local infiltration anesthesia with steroids in total knee arthroplasty: A systematic review of randomized control trials. J Orthop. 2015 Feb 18;12:S44-50. doi: 10.1016/j.jor.2015.01.017. eCollection 2015 Oct. PMID: 26719628; PMCID: PMC4674543.
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J Orthop. 2015 Feb 18;12:S44-50. doi: 10.1016/j.jor.2015.01.017. eCollection 2015 Oct.

Local infiltration anesthesia with steroids in total knee arthroplasty: A systematic review of randomized control trials.

Journal of orthopaedics

Jonathan Tran, Ran Schwarzkopf

Affiliations

  1. Department of Orthopaedic Surgery, Joint Replacement Service, University of California, Irvine, School of Medicine, Orange, CA 92868, USA.

PMID: 26719628 PMCID: PMC4674543 DOI: 10.1016/j.jor.2015.01.017

Abstract

Local infiltration anesthesia (LIA) with anesthetics, steroids, NSAIDS, and epinephrine has been shown to be effective in reducing total knee arthroplasty (TKA) postoperative pain. This systematic review explores the functional outcomes of randomized control trials that have compared the use of LIA with and without steroids during TKA. Five studies with 412 patients met the inclusion criteria, 228 received local infiltration anesthesia with steroids (LIAS) and 184 received local infiltration anesthesia without steroids (LIAWS). The use of LIAS in management of postoperative TKA pain has been shown to decrease the length of hospital stay, time required to achieve straight leg raise, and pro-inflammatory signals in patients. Although there is no overwhelming data to suggest LIAS improves postoperative TKA pain, current literature does support its effectiveness in producing other favorable surgical outcomes.

Keywords: Local infiltration anesthesia; Periarticular injection; Steroid; Systematic review; Total knee arthroplasty

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