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Yi J, Liu W, Chen S, et al. Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation. Light Sci Appl. 2015;4(9)doi: 10.1038/lsa.2015.107.
Yi, J., Liu, W., Chen, S., Backman, V., Sheibani, N., Sorenson, C. M., Fawzi, A. A., Linsenmeier, R. A., & Zhang, H. F. (2015). Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation. Light, science & applications, 4(9), . https://doi.org/10.1038/lsa.2015.107
Yi, Ji, et al. "Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation." Light, science & applications vol. 4,9 (2015). doi: https://doi.org/10.1038/lsa.2015.107
Yi J, Liu W, Chen S, Backman V, Sheibani N, Sorenson CM, Fawzi AA, Linsenmeier RA, Zhang HF. Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation. Light Sci Appl. 2015 Sep;4(9). doi: 10.1038/lsa.2015.107. Epub 2015 Sep 25. PMID: 26658555; PMCID: PMC4674267.
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Light Sci Appl. 2015 Sep;4(9). doi: 10.1038/lsa.2015.107. Epub 2015 Sep 25.

Visible light optical coherence tomography measures retinal oxygen metabolic response to systemic oxygenation.

Light, science & applications

Ji Yi, Wenzhong Liu, Siyu Chen, Vadim Backman, Nader Sheibani, Christine M Sorenson, Amani A Fawzi, Robert A Linsenmeier, Hao F Zhang

Affiliations

  1. Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.
  2. McPherson Eye Research Institute, University of Wisconsin, Madison, WI 53705, USA.
  3. Department of Ophthalmology, Northwestern University, Chicago Illinois 60611, USA.
  4. Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA ; Department of Ophthalmology, Northwestern University, Chicago Illinois 60611, USA ; Department of Neurobiology, Northwestern University, Evanston, IL 60208, USA.
  5. Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA ; Department of Ophthalmology, Northwestern University, Chicago Illinois 60611, USA.

PMID: 26658555 PMCID: PMC4674267 DOI: 10.1038/lsa.2015.107

Abstract

The lack of capability to quantify oxygen metabolism noninvasively impedes both fundamental investigation and clinical diagnosis of a wide spectrum of diseases including all the major blinding diseases such as age-related macular degeneration, diabetic retinopathy, and glaucoma. Using visible light optical coherence tomography (vis-OCT), we demonstrated accurate and robust measurement of retinal oxygen metabolic rate (rMRO

Keywords: oxygen metabolism; retinal circulation; visible light optical coherence tomography

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