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Chen B, Zheng YH, Zheng T, et al. The implantation of a Nickel-Titanium shape memory alloy ameliorates vertebral body compression fractures: a cadaveric study. Int J Clin Exp Med. 2015;8(9):16899-906
Chen, B., Zheng, Y. H., Zheng, T., Sun, C. H., Lu, J., Cao, P., & Zhou, J. H. (2015). The implantation of a Nickel-Titanium shape memory alloy ameliorates vertebral body compression fractures: a cadaveric study. International journal of clinical and experimental medicine, 8(9), 16899-906.
Chen, Bo, et al. "The implantation of a Nickel-Titanium shape memory alloy ameliorates vertebral body compression fractures: a cadaveric study." International journal of clinical and experimental medicine vol. 8,9 (2015): 16899-906.
Chen B, Zheng YH, Zheng T, Sun CH, Lu J, Cao P, Zhou JH. The implantation of a Nickel-Titanium shape memory alloy ameliorates vertebral body compression fractures: a cadaveric study. Int J Clin Exp Med. 2015 Sep 15;8(9):16899-906. eCollection 2015. PMID: 26629241; PMCID: PMC4659129.
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Int J Clin Exp Med. 2015 Sep 15;8(9):16899-906. eCollection 2015.

The implantation of a Nickel-Titanium shape memory alloy ameliorates vertebral body compression fractures: a cadaveric study.

International journal of clinical and experimental medicine

Bo Chen, Yue-Huang Zheng, Tao Zheng, Chang-Hui Sun, Jiong Lu, Peng Cao, Jian-Hua Zhou

Affiliations

  1. Department of Orthopaedics, Rui Jin Hospital, The School of Medicine, Shanghai Jiaotong University, Shanghai Institute of Traumatology and Orthopaedics Shanghai 200025, China.
  2. Department of Orthopaedics, Rui Jin Hospital Lu Wan Branch, The School of Medicine, Shanghai Jiaotong University Shanghai 200025, China.
  3. Department of Orthopaedics, Shanghai Pudong Hospital Shanghai 201399, China.

PMID: 26629241 PMCID: PMC4659129

Abstract

OBJECTIVE: To evaluate the effect of a Nickel-Titanium (Ni-Ti) shape memory alloy in the treatment of vertebral body compression fractures.

METHODS: The experimental thoracic-lumbar fracture units were made with adult human fresh-frozen vertebral specimens. A total of 30 fresh-frozen vertebral units were randomly assigned to 3 experimental groups: control group, percutaneous kyphoplasty group (PKP group), and percutaneous Ni-Ti shape memory alloys implant group (Ni-Ti implant group). Vertebral height and ultimate compression load of the vertebral body before and after procedures were measured to determine the restoration of vertebral heights and compressive strength, respectively.

RESULTS: The Ni-Ti implant group achieved a vertebrae endplate reduction effect comparable to the PKP group. The vertebral height of the PKP group was restored from 2.01±0.21 cm to 2.27±0.18 cm after procedure, whereas that of the Ni-Ti implant group was restored from 2.00±0.18 cm to 2.31±0.17 cm. The ultimate loads of the vertebrae body of the PKP and the Ni-Ti implant groups were 2880.75±126.17 N and 2888.00±144.69 N, respectively, both of which were statistically significantly higher than that of the control group (2017.17±163.71 N). There was no significant difference in ultimate compression load of vertebrae body between the Ni-Ti implant and PKP groups.

CONCLUSIONS: The implantation of Ni-Ti shape memory alloys of vertebral body induced effective endplate reduction, restored vertebral height, and provided immediate biomechanical spinal stability.

Keywords: Ni-Ti shape memory alloys; Osteoporosis; endplate reduction; ultimate load

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