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Chaban V. Estrogen modulation of visceral nociceptors. Curr Trends Neurol. 2013;7:51-55
Chaban, V. (2013). Estrogen modulation of visceral nociceptors. Current trends in neurology, 751-55.
Chaban, Victor. "Estrogen modulation of visceral nociceptors." Current trends in neurology vol. 7 (2013): 51-55.
Chaban V. Estrogen modulation of visceral nociceptors. Curr Trends Neurol. 2013;7:51-55. PMID: 26752851; PMCID: PMC4704695.
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Curr Trends Neurol. 2013;7:51-55.

Estrogen modulation of visceral nociceptors.

Current trends in neurology

Victor Chaban

Affiliations

  1. Department of Internal Medicine, Charles R. Drew University of Medicine and Science, Los Angeles, USA; Department of Medicine, University of California, Los Angeles, USA.

PMID: 26752851 PMCID: PMC4704695

Abstract

A large body of literature supports the idea that estrogen modulates nociceptive responses in pelvic pain syndromes; however, whether this hormone is pro- or anti-nociceptive remains unresolved. The dorsal root ganglion (DRG) is an important site of visceral afferent convergence and cross-sensitization. Within the context of our hypothesis visceral nociception and nociceptor sensitization appear to be regulated by purinergic P2X

Keywords: DRG; P2X; TRPV1; calcium

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