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Lee EL, Bendre HH, Kalmykov A, et al. Surface modification of uniaxial cyclic strain cell culture platform with temperature-responsive polymer for cell sheet detachment. J Mater Chem B. 2015;3(40):7899-7902doi: 10.1039/c5tb01171j.
Lee, E. L., Bendre, H. H., Kalmykov, A., & Wong, J. Y. (2015). Surface modification of uniaxial cyclic strain cell culture platform with temperature-responsive polymer for cell sheet detachment. Journal of materials chemistry. B, 3(40), 7899-7902. https://doi.org/10.1039/c5tb01171j
Lee, E L, et al. "Surface modification of uniaxial cyclic strain cell culture platform with temperature-responsive polymer for cell sheet detachment." Journal of materials chemistry. B vol. 3,40 (2015): 7899-7902. doi: https://doi.org/10.1039/c5tb01171j
Lee EL, Bendre HH, Kalmykov A, Wong JY. Surface modification of uniaxial cyclic strain cell culture platform with temperature-responsive polymer for cell sheet detachment. J Mater Chem B. 2015 Oct 28;3(40):7899-7902. doi: 10.1039/c5tb01171j. Epub 2015 Aug 19. PMID: 26660468; PMCID: PMC4675169.
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J Mater Chem B. 2015 Oct 28;3(40):7899-7902. doi: 10.1039/c5tb01171j. Epub 2015 Aug 19.

Surface modification of uniaxial cyclic strain cell culture platform with temperature-responsive polymer for cell sheet detachment.

Journal of materials chemistry. B

E L Lee, H H Bendre, A Kalmykov, J Y Wong

Affiliations

  1. Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
  2. Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA ; Department of Materials Science and Engineering, Boston University, Boston, MA 02215, USA.

PMID: 26660468 PMCID: PMC4675169 DOI: 10.1039/c5tb01171j

Abstract

Current cell sheet-based blood vessels lack biomimetic structure and require excessively long culture times that may compromise smooth muscle cell phenotype. We modified a commercially available product for uniaxial cell sheet conditioning with thermoresponsive copolymers. Thus, culture of detachable conditioned cell sheets is shortened while retaining structural integrity and contractility.

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