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J Photochem Photobiol A Chem. 2016 Feb 01;316:104-116. doi: 10.1016/j.jphotochem.2015.05.033.

Fluorescence Phenomena in Nerve-Labeling Styryl-Type Dyes.

Journal of photochemistry and photobiology. A, Chemistry

Tiberiu M Siclovan, Rong Zhang, Victoria Cotero, Anshika Bajaj, Dmitry V Dylov, Siavash Yazdanfar, Randall Carter, Cristina A Tan Hehir, Arunkumar Natarajan

Affiliations

  1. GE Global Research, One Research Circle, Niskayuna NY 12309.

PMID: 26693208 PMCID: PMC4683607 DOI: 10.1016/j.jphotochem.2015.05.033

Abstract

Several classes of diversely substituted styryl type dyes have been synthesized with the goal of extending their expected fluorescent properties as much towards red as possible given the constraint that they maintain drug-like properties and retain high affinity binding to their biological target. We report on the synthesis, optical properties of a series of styryl dyes (

Keywords: Styryl dyes; TICT emission; dyes; fluorescence imaging of nerves; in vivo and ex vixo imaging; laparoscopy; nerve labeling

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