J Am Geriatr Soc. 2015 Dec;63(12):2572-2579. doi: 10.1111/jgs.13785. Epub 2015 Dec 11.
Predictors of Mortality Up to 1 Year After Emergency Major Abdominal Surgery in Older Adults.
Journal of the American Geriatrics Society
Zara Cooper, Susan L Mitchell, Rebecca J Gorges, Ronnie A Rosenthal, Stuart R Lipsitz, Amy S Kelley
Affiliations
Affiliations
- Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts.
- Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, Massachusetts.
- Institute for Aging Research, Hebrew Senior Life, Boston, Massachusetts.
- Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
- Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
- Department of Surgery, School of Medicine, Yale University, New Haven, Connecticut.
- James J. Peters Veterans Affairs Medical Center, Bronx, New York.
PMID: 26661929
PMCID: PMC4688175 DOI: 10.1111/jgs.13785
Abstract
OBJECTIVES: To identify factors associated with mortality in older adults 30, 180, and 365 days after emergency major abdominal surgery.
DESIGN: A retrospective study linked to Medicare claims from 2000 to 2010.
SETTING: Health and Retirement Study (HRS).
PARTICIPANTS: Medicare beneficiaries aged 65.5 enrolled in the HRS from 2000 to 2010 with at least one urgent or emergency major abdominal surgery and a core interview from the HRS within 3 years before surgery.
MEASUREMENTS: Survival analysis was used to describe all-cause mortality 30, 180, and 365 days after surgery. Complementary log-log regression was used to identify participant characteristics and postoperative events associated with poorer survival.
RESULTS: Four hundred individuals had one of the urgent or emergency surgeries of interest, 24% of whom were aged 85 and older, 50% had coronary artery disease, 48% had cancer, 33% had congestive heart failure, and 37% experienced a postoperative complication. Postoperative mortality was 20% at 30 days, 31% at 180 days, and 34% at 365 days. Of those aged 85 and older, 50% were dead 1 year after surgery. After multivariate adjustment including postoperative complications, dementia (hazard ratio (HR) = 2.02, 95% confidence interval (CI) = 1.24-3.31), hospitalization within 6 months before surgery (HR = 1.63, 95% CI = 1.12-2.28), and complications (HR = 3.45, 95% CI = 2.32-5.13) were independently associated with worse 1-year survival.
CONCLUSION: Overall mortality is high in many older adults up to 1 year after undergoing emergency major abdominal surgery. The occurrence of a complication is the clinical factor most strongly associated with worse survival.
© 2015, Copyright the Authors Journal compilation © 2015, The American Geriatrics Society.
Keywords: 1-year mortality; emergency surgery; geriatric surgery; major abdominal surgery; surgical complications
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