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Settem JV, Trivedi S, Kamath AG, et al. Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil. Indian J Psychol Med. 2015;37(3):358-9doi: 10.4103/0253-7176.162925.
Settem, J. V., Trivedi, S., Kamath, A. G., Behere, R. V., Kanaradi, H., & Bhat, S. M. (2015). Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil. Indian journal of psychological medicine, 37(3), 358-9. https://doi.org/10.4103/0253-7176.162925
Settem, Jagadeesh V V, et al. "Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil." Indian journal of psychological medicine vol. 37,3 (2015): 358-9. doi: https://doi.org/10.4103/0253-7176.162925
Settem JV, Trivedi S, Kamath AG, Behere RV, Kanaradi H, Bhat SM. Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil. Indian J Psychol Med. 2015 Jul-Sep;37(3):358-9. doi: 10.4103/0253-7176.162925. PMID: 26664091; PMCID: PMC4649798.
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Indian J Psychol Med. 2015 Jul-Sep;37(3):358-9. doi: 10.4103/0253-7176.162925.

Clozapine-induced Supraventricular Tachycardia and its Treatment with Verapamil.

Indian journal of psychological medicine

Jagadeesh V V Settem, Satyakant Trivedi, Avinash G Kamath, Rishikesh V Behere, Haridas Kanaradi, Sripathy M Bhat

Affiliations

  1. Department of Psychiatry, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.

PMID: 26664091 PMCID: PMC4649798 DOI: 10.4103/0253-7176.162925

Abstract

Clozapine is known to be an effective antipsychotic for schizophrenia. Cardiovascular complications associated with initiation of clozapine include tachycardia, postural hypotension, and myocarditis. Factors associated with development of cardiovascular adverse events are not clearly known, and dose titration has been described to be one among the associated risk factors. We report a case of a 45-year-old man with treatment resistant schizophrenia who developed supraventricular tachycardia during initiation of clozapine and discuss the role of verapamil in its successful management.

Keywords: Clozapine; schizophrenia; supraventricular tachycardia; verapamil

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