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Chirico V, Lacquaniti A, Vinci S, et al. HIGH-MOBILITY GROUP BOX 1 IN ALLERGIC AND NON ALLERGIC UPPER AIRWAY INFLAMMATION. J Biol Regul Homeost Agents. 2015;29(2):55-7
Chirico, V., Lacquaniti, A., Vinci, S., Piraino, B., Manti, S., Marseglia, L., Salpietro, A., Gitto, E., Arrigo, T., Salpietro, C., & Cuppari, C. (2015). HIGH-MOBILITY GROUP BOX 1 IN ALLERGIC AND NON ALLERGIC UPPER AIRWAY INFLAMMATION. Journal of biological regulators and homeostatic agents, 29(2), 55-7.
Chirico, V, et al. "HIGH-MOBILITY GROUP BOX 1 IN ALLERGIC AND NON ALLERGIC UPPER AIRWAY INFLAMMATION." Journal of biological regulators and homeostatic agents vol. 29,2 (2015): 55-7.
Chirico V, Lacquaniti A, Vinci S, Piraino B, Manti S, Marseglia L, Salpietro A, Gitto E, Arrigo T, Salpietro C, Cuppari C. HIGH-MOBILITY GROUP BOX 1 IN ALLERGIC AND NON ALLERGIC UPPER AIRWAY INFLAMMATION. J Biol Regul Homeost Agents. 2015 Apr-Jun;29(2):55-7. PMID: 26634588.
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J Biol Regul Homeost Agents. 2015 Apr-Jun;29(2):55-7.

HIGH-MOBILITY GROUP BOX 1 IN ALLERGIC AND NON ALLERGIC UPPER AIRWAY INFLAMMATION.

Journal of biological regulators and homeostatic agents

V Chirico, A Lacquaniti, S Vinci, B Piraino, S Manti, L Marseglia, A Salpietro, E Gitto, T Arrigo, C Salpietro, C Cuppari

Affiliations

  1. Department of Pediatric Sciences, Unit of Pediatric Genetics and Immunology, University of Messina, Italy.
  2. Department of Internal Medicine, University of Messina, Messina, Italy.

PMID: 26634588

Abstract

High mobility group box 1, an evolutionary ancient protein conserved in the eukaryotic kingdom, exerts intra- and extra- cellular functions, orchestrating a homeostatic defensive response in challenged tissues. Its action associated with various inflammatory cells is essential for the occurrence, progression, and persistence of asthma, rhinitis, and nasal polyposis. The recent discovery of High mobility group box 1, as a critical mediator of inflammation, stimulated an increasing interest in the field of inflammation research, suggesting new therapies for atopic and non-atopic inflammatory processes.

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