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Opt Express. 2015 Nov 16;23(23):30204-15. doi: 10.1364/OE.23.030204.

Measurement of the light scattering of single micrometer-sized particles captured with a microfluidic trap.

Optics express

Jie Dai, Wei Li, Baoyu Gong, Huimin Wang, Min Xia, Kecheng Yang

PMID: 26698501 DOI: 10.1364/OE.23.030204

Abstract

Light scattering detection of a single particle is significant to both theoretical developments and application progresses of particle scattering. In this work, a new method employing the polydimethylsiloxane microfluidic catcher with self-regulation was developed to detect the light scattering of an individual micro particle (20.42, 23.75, and 31.10 μm) in a wide angular range. This system can rapidly (<2 min) immobilize single particles without aggregations and continuously analyze its light scattering ranging from 2° to 162°. The high success ratio of the capture, good agreement with the anticipation, and moderate time and cost make this method a promising candidate in single-particle-scattering applications.

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