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Gastroenterol Res Pract. 2015;2015:159641. doi: 10.1155/2015/159641. Epub 2015 Nov 22.

Assessment of Disease Activity in Small Bowel Crohn's Disease: Comparison between Endoscopy and Magnetic Resonance Enterography Using MRIA and Modified MRIA Score.

Gastroenterology research and practice

Arnaldo Scardapane, Annalisa Ambrosi, Emanuela Salinaro, Maria Elisabetta Mancini, Mariabeatrice Principi, Alfredo Di Leo, Filomenamila Lorusso, Amato Antonio Stabile Ianora, Giuseppe Angelelli

Affiliations

  1. Section of Diagnostic Imaging, Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", Piazza Giulio Cesare 11, 70124 Bari, Italy.
  2. Section of Gastroenterology, Department of Emergency and Organ Transplantation, University of Bari "Aldo Moro", Piazza Giulio Cesare 11, 70124 Bari, Italy.

PMID: 26759554 PMCID: PMC4670649 DOI: 10.1155/2015/159641

Abstract

Objectives. To retrospectively compare the results of the MRIA (magnetic resonance index of activity) with a modified MRIA (mMRIA), which was calculated excluding from MRIA formula the data of relative contrast enhancement (RCE). Materials and Methods. MR-E and corresponding endoscopic records of 100 patients were reviewed. MRIA, mMRIA, and SES endoscopic index were calculated for all the patients. Namely, MRIA was calculated as follows: (1.5 × wall thickening + 0.02 × RCE + 5 × intramural edema + 10 × ulcers), while mMRIA was calculated with the modified formula (1.5 × wall thickening + 5 × intramural edema + 10 × ulcers). Results. Mean MRIA and mMRIA values were 19.3 and 17.68, respectively (p < 0.0001). A significant correlation (p < 0.0001) was observed between MRIA and mMRIA scores and between both MR indexes and SES (p < 0.0001). Conclusions. mMRIA was comparable to MRIA in the evaluation of disease activity in Crohn's disease.

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