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World J Cardiol. 2015 Nov 26;7(11):801-7. doi: 10.4330/wjc.v7.i11.801.

Comparison of echocardiography and device based algorithm for atrio-ventricular delay optimization in heart block patients.

World journal of cardiology

Rajesh Vijayvergiya, Ankur Gupta

Affiliations

  1. Rajesh Vijayvergiya, Ankur Gupta, Department of Cardiology, Advanced Cardiac Centre, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.

PMID: 26635928 PMCID: PMC4660475 DOI: 10.4330/wjc.v7.i11.801

Abstract

AIM: To compare the atrio-ventricular (AV/PV) delay optimization by echocardiography and intra-cardiac electrocardiogram (IEGM) based QuickOpt algorithm in complete heart block (CHB) patients, implanted with a dual chamber pacemaker.

METHODS: We prospectively enrolled 20 patients (age 59.45 ± 18.1 years; male: 65%) with CHB, who were implanted with a dual chamber pacemaker. The left ventricular outflow tract velocity time-integral was measured after AV/PV delay optimization by both echocardiography and QuickOpt algorithm method. Bland-Altman analysis was used for agreement between the two techniques.

RESULTS: The optimal AV and PV delay determined by echocardiography was 155.5 ± 14.68 ms and 122.5 ± 17.73 ms (P < 0.0001), respectively and by QuickOpt method was 167.5 ± 16.73 and 117.5 ms ± 9.10 ms (P < 0.0001), respectively. A good agreement was observed between optimal AV and PV delay as measured by two methods. However, the correlation of the optimal AV (r = 0.0689, P = 0.77) and PV (r = 0.2689, P = 0.25) intervals measured by the two techniques was poor. The time required for AV/PV optimization was 45.26 ± 1.73 min by echocardiography and 0.44 ± 0.08 min by QuickOpt method (P < 0.0001).

CONCLUSION: The programmer based IEGM method is an automated, quick, easier and reliable alternative to echocardiography for the optimization of AV/PV delay in CHB patients, implanted with a dual chamber pacemaker.

Keywords: Atrio-ventricular delay optimization; Complete heart block; Doppler echocardiography; Dual chamber pacemaker; Hemodynamics; QuickOpt algorithm

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