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Loh PH, Bourantas CV, Chan PH, et al. Catheter-based intervention for symptomatic patient with severe mitral regurgitation and very poor left ventricular systolic function - Safe but no room for complacency. World J Cardiol. 2015;7(11):817-21doi: 10.4330/wjc.v7.i11.817.
Loh, P. H., Bourantas, C. V., Chan, P. H., Ihlemann, N., Gustafsson, F., Clark, A. L., Price, S., Mario, C. D., Moat, N., Alamgir, F., Estevez-Loureiro, R., Søndergaard, L., & Franzen, O. (2015). Catheter-based intervention for symptomatic patient with severe mitral regurgitation and very poor left ventricular systolic function - Safe but no room for complacency. World journal of cardiology, 7(11), 817-21. https://doi.org/10.4330/wjc.v7.i11.817
Loh, Poay Huan, et al. "Catheter-based intervention for symptomatic patient with severe mitral regurgitation and very poor left ventricular systolic function - Safe but no room for complacency." World journal of cardiology vol. 7,11 (2015): 817-21. doi: https://doi.org/10.4330/wjc.v7.i11.817
Loh PH, Bourantas CV, Chan PH, Ihlemann N, Gustafsson F, Clark AL, Price S, Mario CD, Moat N, Alamgir F, Estevez-Loureiro R, Søndergaard L, Franzen O. Catheter-based intervention for symptomatic patient with severe mitral regurgitation and very poor left ventricular systolic function - Safe but no room for complacency. World J Cardiol. 2015 Nov 26;7(11):817-21. doi: 10.4330/wjc.v7.i11.817. PMID: 26635930; PMCID: PMC4660477.
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World J Cardiol. 2015 Nov 26;7(11):817-21. doi: 10.4330/wjc.v7.i11.817.

Catheter-based intervention for symptomatic patient with severe mitral regurgitation and very poor left ventricular systolic function - Safe but no room for complacency.

World journal of cardiology

Poay Huan Loh, Christos V Bourantas, Pak Hei Chan, Nikolaj Ihlemann, Fin Gustafsson, Andrew L Clark, Susanna Price, Carlo Di Mario, Neil Moat, Farqad Alamgir, Rodrigo Estevez-Loureiro, Lars Søndergaard, Olaf Franzen

Affiliations

  1. Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore.

PMID: 26635930 PMCID: PMC4660477 DOI: 10.4330/wjc.v7.i11.817

Abstract

Many patients with left ventricular systolic dysfunction have concomitant mitral regurgitation (MR). Their symptoms and prognosis worsen with increasing severity of MR. Percutaneous MitraClip(®) can be used safely to reduce the severity of MR even in patients with advanced heart failure and is associated with improved symptoms, quality of life and exercise tolerance. However, a few patients with very poor left ventricular systolic function may experience significant haemodynamic disturbance in the peri-procedural period. We present three such patients, highlighting some of the potential problems encountered and discuss their possible pathophysiological mechanisms and safety measures.

Keywords: Chronic heart failure; Left ventricular systolic dysfunction; MitraClip; Mitral regurgitation; Mitral valve; Percutaneous

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