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Duarte PA, Bredt CS, Bredt GL, et al. Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure. Einstein (Sao Paulo). 2011;9(1):52-5doi: 10.1590/S1679-45082011AO1878.
Duarte, P. A., Bredt, C. S., Bredt, G. L., Jorge, A. C., Venazzi, A., Tondo, L. G., Oliveira, L. S., Jorge, M. M., Marchiori, R., Giancursi, T. S., Coradin, M., & Alexandrino, A. G. (2011). Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure. Einstein (Sao Paulo, Brazil), 9(1), 52-5. https://doi.org/10.1590/S1679-45082011AO1878
Duarte, Péricles Almeida Delfino, et al. "Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure." Einstein (Sao Paulo, Brazil) vol. 9,1 (2011): 52-5. doi: https://doi.org/10.1590/S1679-45082011AO1878
Duarte PA, Bredt CS, Bredt GL, Jorge AC, Venazzi A, Tondo LG, Oliveira LS, Jorge MM, Marchiori R, Giancursi TS, Coradin M, Alexandrino AG. Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure. Einstein (Sao Paulo). 2011 Mar;9(1):52-5. doi: 10.1590/S1679-45082011AO1878. Portuguese. PMID: 26760553.
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Einstein (Sao Paulo). 2011 Mar;9(1):52-5. doi: 10.1590/S1679-45082011AO1878.

Procalcitonin in patients with influenza A (H1N1) infection and acute respiratory failure.

Einstein (Sao Paulo, Brazil)

[Article in Portuguese]
Péricles Almeida Delfino Duarte, Carla Sakuma de Oliveira Bredt, Gerson Luís Bredt, Amaury César Jorge, Alisson Venazzi, Leônidas Gustavo Tondo, Luciana Schmidt Cardon de Oliveira, Marcela Maria Jorge, Roberta Marchiori, Thiago Simões Giancursi, Marcelo Coradin, Anderson Gustavo Alexandrino

Affiliations

  1. Departament of Emergency and Intensive Medicine, Universidade Estadual do Oeste do Paraná, Cascavel, PR, BR.
  2. Department of Internal Medicine, Universidade Estadual do Oeste do Paraná, Cascavel, PR, BR.

PMID: 26760553 DOI: 10.1590/S1679-45082011AO1878

Abstract

OBJECTIVE: To verify serum procalcitonin levels of patients with acute respiratory failure secondary to influenza A (H1N1) upon their admission to the Intensive Care Unit and to compare these results to values found in patients with sepsis and trauma admitted to the same unit.

METHODS: Analysis of records of patients infected with influenza A (H1N1) and respiratory failure admitted to the General Intensive Care Unit during in a period of 60 days. The values of serum procalcitonin and clinical and laboratory data were compared to those of all patients admitted with sepsis or trauma in the previous year.

RESULTS: Among patients with influenza A (H1N1) (n = 16), the median serum procalcitonin level upon admission was 0.11 ng/mL, lower than in the sepsis group (p < 0.001) and slightly lower than in trauma patients. Although the mean values were low, serum procalcitonin was a strong predictor of hospital mortality in patients with influenza A (H1N1).

CONCLUSION: Patients with influenza A (H1N1) with severe acute respiratory failure presented with low serum procalcitonin values upon admission, although their serum levels are predictors of hospital mortality. The kinetics study of this biomarker may be a useful tool in the management of this group of patients.

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